Machiko Nishio
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Explore the profile of Machiko Nishio including associated specialties, affiliations and a list of published articles.
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Articles
66
Citations
608
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Recent Articles
1.
Ohta K, Saka N, Nishio M
J Virol
. 2024 Oct;
98(11):e0144624.
PMID: 39480088
Importance: We sought to identify the important residues for RNA binding of nairovirus nucleoprotein using Orthonairovirus hazaraense, a surrogate model for Orthonairovirus haemorrhagiae. The four basic amino acid residues of...
2.
Human parainfluenza virus type 2 V protein inhibits mitochondrial apoptosis pathway through two ways
Saka N, Nishio M, Ohta K
Virology
. 2024 Mar;
594:110053.
PMID: 38492518
Paramyxoviruses are reported to block apoptosis for their replication, but the mechanisms remain unclear. Furthermore, regulation of mitochondrial apoptosis by paramyxoviruses has been hardly reported. We investigated whether and how...
3.
Ohta K, Saka N, Nishi Y, Nishio M
J Virol
. 2024 Feb;
98(3):e0169823.
PMID: 38358288
Importance: We investigated whether and how nairoviruses persistently infect human cells, using Hazara orthonairovirus (HAZV), a surrogate model for Crimean-Congo hemorrhagic fever virus. We established a human cell line that...
4.
Saka N, Ohta K, Kolakofsky D, Nishio M
J Virol
. 2023 Nov;
97(11):e0091823.
PMID: 37916836
The realization that segmented negative-strand RNA virus genome ribonucleoproteins are never free as their RNA ends are always bound to the viral polymerase has highlighted the problem of how these...
5.
Ohta K, Saka N, Fukasawa M, Nishio M
Front Microbiol
. 2023 Jun;
14:1192956.
PMID: 37287449
Background: Tight junctions act as a barrier that prevents invasion of pathogens through epithelial cells. This study aims to elucidate the correlation between tight junctions and nairoviruses using Hazara orthonairovirus...
6.
Ohta K, Saka N, Nishio M
Viruses
. 2022 Sep;
14(9).
PMID: 36146771
Viruses have evolved various strategies to evade the host innate immune system. The relationship between nairoviruses and the interferon (IFN) system is poorly understood. We investigated whether and how nairoviruses...
7.
Kolakofsky D, Le Mercier P, Nishio M, Blackledge M, Crepin T, Ruigrok R
Viruses
. 2021 Dec;
13(12).
PMID: 34960735
Vesicular stomatitis virus (VSV), the founding member of the mononegavirus order (), was found to be a negative strand RNA virus in the 1960s, and since then the number of...
8.
Saka N, Matsumoto Y, Ohta K, Kolakofsky D, Nishio M
J Virol
. 2021 Dec;
96(4):e0206721.
PMID: 34878809
Paramyxovirus genomes, like that of human parainfluenza virus type 2 (hPIV2), have lengths of precisely multiples-of-six nucleotides ("rule of six"), where each nucleoprotein subunit (NP) binds exactly six nucleotides. Ten...
9.
Ohta K, Saka N, Nishio M
J Virol
. 2021 Jan;
95(6).
PMID: 33408172
Intracellular iron concentration is tightly controlled for cell viability. It is known to affect the growth of several viruses, but the molecular mechanisms are not well understood. We found that...
10.
Miyamoto K, Yonemitsu T, Tanaka R, Nakashima T, Shibata M, Funahashi R, et al.
Acute Med Surg
. 2020 Jun;
7(1):e521.
PMID: 32566237
Background: Coronavirus disease (COVID-19) is a growing concern worldwide. Approximately 5% of COVID-19 cases require intensive care. However, the optimal treatment for respiratory failure in COVID-19 patients is yet to...