M Whirl-Carrillo
Overview
Explore the profile of M Whirl-Carrillo including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
2036
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0
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Recent Articles
1.
Jeiziner C, Suter K, Wernli U, Barbarino J, Gong L, Whirl-Carrillo M, et al.
Pharmacogenomics J
. 2020 Oct;
21(4):423-434.
PMID: 33070160
Implementation of pharmacogenetics (PGx) and individualization of drug therapy is supposed to obviate adverse drug reactions or therapy failure. Health care professionals (HCPs) use drug labels (DLs) as reliable information...
2.
Bank P, Caudle K, Swen J, Gammal R, Whirl-Carrillo M, Klein T, et al.
Clin Pharmacol Ther
. 2017 Oct;
103(4):599-618.
PMID: 28994452
Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and Dutch Pharmacogenetics Working Group provide therapeutic recommendations for well-known gene-drug pairs. Published recommendations show a high rate of concordance. However, as a...
3.
Johnson J, Caudle K, Gong L, Whirl-Carrillo M, Stein C, Scott S, et al.
Clin Pharmacol Ther
. 2017 Feb;
102(3):397-404.
PMID: 28198005
This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published literature is presented for...
4.
Luzum J, Pakyz R, Elsey A, Haidar C, Peterson J, Whirl-Carrillo M, et al.
Clin Pharmacol Ther
. 2017 Jan;
102(3):502-510.
PMID: 28090649
Numerous pharmacogenetic clinical guidelines and recommendations have been published, but barriers have hindered the clinical implementation of pharmacogenetics. The Translational Pharmacogenetics Program (TPP) of the National Institutes of Health (NIH)...
5.
Bell G, Caudle K, Whirl-Carrillo M, Gordon R, Hikino K, Prows C, et al.
Clin Pharmacol Ther
. 2016 Dec;
102(2):213-218.
PMID: 28002639
No abstract available.
6.
Whirl-Carrillo M, Sangkuhl K, Gong L, Klein T
Clin Pharmacol Ther
. 2016 Jul;
100(6):600-602.
PMID: 27367543
Significant advances have been made in the clinical implementation of pharmacogenomics in recent years with tools for clinical decision support (CDS) being developed and integrated in the electronic health record...
7.
Kalman L, Agundez J, Appell M, Black J, Bell G, Boukouvala S, et al.
Clin Pharmacol Ther
. 2015 Oct;
99(2):172-85.
PMID: 26479518
This article provides nomenclature recommendations developed by an international workgroup to increase transparency and standardization of pharmacogenetic (PGx) result reporting. Presently, sequence variants identified by PGx tests are described using...
8.
Gammal R, Court M, Haidar C, Iwuchukwu O, Gaur A, Alvarellos M, et al.
Clin Pharmacol Ther
. 2015 Sep;
99(4):363-9.
PMID: 26417955
The antiretroviral protease inhibitor atazanavir inhibits hepatic uridine diphosphate glucuronosyltransferase (UGT) 1A1, thereby preventing the glucuronidation and elimination of bilirubin. Resultant indirect hyperbilirubinemia with jaundice can cause premature discontinuation of...
9.
McDonagh E, Whirl-Carrillo M, Altman R, Klein T
Clin Pharmacol Ther
. 2015 Feb;
97(2):116-9.
PMID: 25670512
As pharmacogenomics becomes integrated into clinical practice, curation of published studies becomes increasingly important. At the Pharmacogenomics Knowledgebase (PharmGKB; www.pharmgkb.org), pharmacogenetic associations reported in published articles are manually curated and...
10.
Caudle K, Rettie A, Whirl-Carrillo M, Smith L, Mintzer S, Lee M, et al.
Clin Pharmacol Ther
. 2014 Aug;
96(5):542-8.
PMID: 25099164
Phenytoin is a widely used antiepileptic drug with a narrow therapeutic index and large interpatient variability, partly due to genetic variations in the gene encoding cytochrome P450 (CYP)2C9 (CYP2C9). Furthermore,...