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M van der Paardt

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Recent Articles
1.
van Halm V, van Denderen J, Peters M, Twisk J, van der Paardt M, van der Horst-Bruinsma I, et al.
Ann Rheum Dis . 2006 Apr; 65(11):1473-7. PMID: 16644785
Background: Cardiovascular mortality is increased in patients with ankylosing spondylitis. A possible explanation might be a more prevalent atherogenic lipid profile in patients with ankylosing spondylitis than in the general...
2.
van Denderen J, van der Paardt M, Nurmohamed M, de Ryck Y, Dijkmans B, van der Horst-Bruinsma I
Ann Rheum Dis . 2005 May; 64(12):1761-4. PMID: 15901634
Objective: To assess the efficacy and safety of leflunomide in active ankylosing spondylitis (AS) compared with placebo in a 24 week pilot study. Methods: In a single centre randomised, double...
3.
van der Paardt M, Crusius J, Garcia-Gonzalez M, Dijkmans B, Pena A, van der Horst-Bruinsma I
Ann Rheum Dis . 2005 Mar; 64(4):616-9. PMID: 15769917
Background: Genetic factors are thought to be crucial in the pathogenesis of ankylosing spondylitis. Transforming growth factor beta 1 (TGF beta 1) is a multifunctional cytokine that plays a key...
4.
van der Paardt M, Crusius J, de Koning M, Morre S, van de Stadt R, Dijkmans B, et al.
Ann Rheum Dis . 2005 Jan; 64(2):235-8. PMID: 15647432
Objectives: Ankylosing spondylitis (AS) is a multifactorial and polygenic disease. Apart from HLA, other genes very probably play a role in disease susceptibility. Indigenous bacteria of the gastrointestinal flora appear...
5.
van der Paardt M, Crusius J, de Koning M, Murillo L, van de Stadt R, Dijkmans B, et al.
Genes Immun . 2003 Feb; 4(1):77-8. PMID: 12595906
An insertion mutation at nucleotide 3020 (3020insC) and a missense mutation G2722C in the CARD15 gene on chromosome 16p have been reported to be associated with Crohn's disease (CD). The...
6.
van der Paardt M, Crusius J, Garcia-Gonzalez M, Baudoin P, Kostense P, Alizadeh B, et al.
Rheumatology (Oxford) . 2002 Dec; 41(12):1419-23. PMID: 12468823
Objective: Since ulcerative colitis and Crohn's disease, which are associated with ankylosing spondylitis (AS), have been found to be variably associated with the IL-1B and the IL-1RN genes encoding interleukin-1beta...
7.
van der Paardt M, van Denderen J, van den Brule A, Morre S, van der Horst-Bruinsma I, Bezemer P, et al.
Ann Rheum Dis . 2000 Mar; 59(4):300-2. PMID: 10733479
Objective: To compare the prevalence of Chlamydia trachomatis infections in ankylosing spondylitis (AS) patients with controls, using DNA amplification assays in urine specimens. Methods: The prevalence of C trachomatis infections...