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M Tessema

Explore the profile of M Tessema including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 139
Followers 0
Related Specialties
Oncology
Chemistry
Molecular Biology
Top 10 Co-Authors
S A Belinsky
D M Klinge
T Solomon
L Gorton
C M Yingling
T Ruzgas
E Csoregi
K Do
A M Bernauer
L Van Neste
Published In
Oncogene
Anal Chem
Leukemia
J Fluoresc
Br J Cancer
Affiliations
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Recent Articles
1.
Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model
Reed M, Tellez C, Grimes M, Picchi M, Tessema M, Cheng Y, et al.
Br J Cancer . 2013 Sep; 109(7):1775-81. PMID: 24045660
Background: Epigenetic silencing by promoter methylation and chromatin remodelling affects hundreds of genes and is a causal event for lung cancer. Treatment of patients with low doses of the demethylating...
2.
SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15
Tessema M, Yingling C, Thomas C, Klinge D, Bernauer A, Liu Y, et al.
Oncogene . 2011 Dec; 31(37):4107-16. PMID: 22158045
The heparan sulfate 6-O-endosulfatase (SULF2) promotes growth and metastasis of solid tumors. We recently identified that cytosine methylation of the SULF2 promoter is associated with better survival of resected lung...
3.
Solvent polarity and excitation wavelength dependence of the dual fluorescence in N,N-diethyl-4-nitrosoaniline
Hussien N, Mohammed A, Tessema M, Dejene F, Redi-Abshiro M
J Fluoresc . 2011 Sep; 22(1):451-6. PMID: 21938388
Dual fluorescence in N,N-Diethyl-4-nitrosoaniline (DENA) has been studied employing absorption, excitation and emission spectroscopic techniques and computational methods. The absorption and fluorescence spectra of DENA were measured in solvents of...
4.
LC-Biosensor System for the Determination of the Neurotoxin β-N-Oxalyl-l-α,β-diaminopropionic Acid
Belay A, Ruzgas T, Csoregi E, Moges G, Tessema M, Solomon T, et al.
Anal Chem . 2011 Jun; 69(17):3471-5. PMID: 21639270
An analysis system is described for the determination of the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid (β-ODAP). The system is based on liquid chromatographic separation of β-ODAP from interfering amino acids on an...
5.
Oligosaccharide dehydrogenase-modified graphite electrodes for the amperometric determination of sugars in a flow injection system
Tessema M, Csoregi E, Ruzgas T, Kenausis G, Solomon T, Gorton L
Anal Chem . 2011 Jun; 69(19):4039-44. PMID: 21639213
Enzyme electrodes for the determination of sugars based on solid graphite electrodes modified with oligosaccharide dehydrogenase "wired" with an osmium-based one-electron (no proton) acceptor redox hydrogel were studied as sensors...
6.
Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis
Tessema M, Klinge D, Yingling C, Do K, Van Neste L, Belinsky S
Oncogene . 2010 Jun; 29(37):5159-70. PMID: 20562917
Chemokines are important regulators of directional cell migration and tumor metastasis. A genome-wide transcriptome array designed to uncover novel genes silenced by methylation in lung cancer identified the CXC-subfamily of...
7.
Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML)
Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U
Leukemia . 2003 May; 17(5):910-8. PMID: 12750705
The important cell cycle regulatory gene p15(INK4b) has been shown to be inactivated in acute myeloid leukemia and myelodysplastic syndrome. Little is known about the expression and epigenetic modification of...