M T Flaherty
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Explore the profile of M T Flaherty including associated specialties, affiliations and a list of published articles.
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7
Citations
253
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Recent Articles
1.
A novel kinase activity associated with Nef derived from neurovirulent simian immunodeficiency virus
Barber S, Flaherty M, Plafker S, Clements J
Virology
. 1998 Nov;
251(1):165-75.
PMID: 9813212
The Nef proteins of Simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) have been shown to associate with several cellular kinases. Further, the ability of SIVmac239 Nef to associate...
2.
Flaherty M, Barber S, Clements J
AIDS Res Hum Retroviruses
. 1998 Feb;
14(2):163-70.
PMID: 9462927
We have demonstrated that a molecular clone, SIV/17E-Fr, is neurovirulent in vivo and molecular analyses of this virus in primary macrophages and neuroendothelial cells mapped the domains critical for this...
3.
Mankowski J, Flaherty M, Spelman J, Hauer D, Didier P, Amedee A, et al.
J Virol
. 1997 Aug;
71(8):6055-60.
PMID: 9223498
To examine the relationship between macrophage tropism and neurovirulence, macaques were inoculated with two recombinant hybrid viruses derived from the parent viruses SIVmac239, a lymphocyte-tropic, non-neurovirulent clone, and SIV/17E-Br, a...
4.
Flaherty M, Hauer D, Mankowski J, Zink M, Clements J
J Virol
. 1997 Aug;
71(8):5790-8.
PMID: 9223467
To identify the molecular determinants of neurovirulence, we constructed an infectious simian immunodeficiency virus (SIV) molecular clone, SIV/17E-Fr, that contained the 3' end of a neurovirulent strain of SIV, SIV/17E-Br,...
5.
Threadgill D, Steagall W, Flaherty M, Fuller F, Perry S, Rushlow K, et al.
J Virol
. 1993 May;
67(5):2592-600.
PMID: 8386267
The putative dUTPase domain was deleted from the polymerase (pol) gene of equine infectious anemia virus (EIAV) to produce a recombinant delta DUpol Escherichia coli expression cassette and a delta...
6.
Perry S, Flaherty M, Kelley M, Clabough D, Tronick S, COGGINS L, et al.
J Virol
. 1992 Jul;
66(7):4085-97.
PMID: 1318398
Virulent, wild-type equine infectious anemia virus (EIAV) is restricted in one or more early steps in replication in equine skin fibroblast cells compared with cell culture-adapted virus, which is fully...
7.
Clabough D, Gebhard D, Flaherty M, Whetter L, Perry S, COGGINS L, et al.
J Virol
. 1991 Nov;
65(11):6242-51.
PMID: 1717720
An adult horse infected with a virulent, cell culture-adapted strain of equine infectious anemia virus (EIAV) developed cyclical thrombocytopenia in which the nadir of platelet counts coincided with peak febrile...