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M Slifstein

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Articles 17
Citations 980
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Recent Articles
1.
Weinstein J, van de Giessen E, Rosengard R, Xu X, Ojeil N, Brucato G, et al.
Mol Psychiatry . 2017 Nov; PMID: 29155803
This corrects the article DOI: 10.1038/mp.2017.107.
2.
Weinstein J, van de Giessen E, Rosengard R, Xu X, Ojeil N, Brucato G, et al.
Mol Psychiatry . 2017 May; 23(6):1506-1511. PMID: 28507321
Recent genetic, molecular and post-mortem studies suggest impaired dopamine (DA)-D2 receptor (D2R) trafficking in patients with schizophrenia (SZ). Imaging and preclinical studies have shown agonist-induced D2R internalization can be imaged...
3.
van de Giessen E, Weinstein J, Cassidy C, Haney M, Dong Z, Ghazzaoui R, et al.
Mol Psychiatry . 2016 Mar; 22(1):68-75. PMID: 27001613
Most drugs of abuse lead to a general blunting of dopamine release in the chronic phase of dependence, which contributes to poor outcome. To test whether cannabis dependence is associated...
4.
Poels E, Kegeles L, Kantrowitz J, Slifstein M, Javitt D, Lieberman J, et al.
Mol Psychiatry . 2013 Oct; 19(1):20-9. PMID: 24166406
Currently, all treatments for schizophrenia (SCZ) function primarily by blocking D(2)-type dopamine receptors. Given the limitations of these medications, substantial efforts have been made to identify alternative neurochemical targets for...
5.
Thompson J, Urban N, Slifstein M, Xu X, Kegeles L, Girgis R, et al.
Mol Psychiatry . 2012 Aug; 18(8):909-15. PMID: 22869037
Dopamine (DA) has a role in the pathophysiology of schizophrenia and addiction. Imaging studies have indicated that striatal DA release is increased in schizophrenia, predominantly in the precommissural caudate (preDCA),...
6.
Slifstein M, Kolachana B, Simpson E, Tabares P, Cheng B, DuVall M, et al.
Mol Psychiatry . 2008 Mar; 13(8):821-7. PMID: 18317466
A common polymorphism (val158met) in the gene encoding catechol-O-methyltransferase (COMT) has been shown to affect dopamine (DA) tone in cortex and cortical functioning. D1 receptors are the main DA receptors...
7.
Frankle W, Gil R, Hackett E, Mawlawi O, Zea-Ponce Y, Zhu Z, et al.
Psychopharmacology (Berl) . 2004 Apr; 175(4):473-80. PMID: 15083259
Rationale: To examine the D2 occupancy of two commonly used antipsychotic medications and relate this to the D2 occupancy by endogenous dopamine in schizophrenia. Objectives: The aim of this study...
8.
Mawlawi O, Martinez D, Slifstein M, Broft A, Chatterjee R, Hwang D, et al.
J Cereb Blood Flow Metab . 2001 Aug; 21(9):1034-57. PMID: 11524609
Dopamine transmission in the ventral striatum (VST), a structure which includes the nucleus accumbens, ventral caudate, and ventral putamen, plays a critical role in the pathophysiology of psychotic states and...
9.
Slifstein M, Laruelle M
Nucl Med Biol . 2001 Aug; 28(5):595-608. PMID: 11516703
The science of quantitative analysis of PET and SPECT neuroreceptor imaging studies has grown considerably over the past decade. A number of methods have been proposed in which receptor parameter...
10.
Zarahn E, Slifstein M
Neuroimage . 2001 Aug; 14(3):768-79. PMID: 11506549
In fMRI, the issues involved in the control of type I error are fairly well understood. In contrast, the control of type II error has received less formal attention. This...