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M Rubenstein

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Articles 109
Citations 313
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Recent Articles
1.
Anderson K, Guinan P, Rubenstein M
Med Oncol . 2013 Dec; 31(1):779. PMID: 24323398
A CD44/a 2 B 1- (CD41 integrin) and B-catenin-labeled fraction of PC3 prostate cancer cells is able to reconstitute cells representative of the original tumor in immuno-deficient mice (Li et...
2.
Anderson K, Guinan P, Rubenstein M
Anticancer Res . 2011 Mar; 31(2):487-94. PMID: 21378328
It has been reported that human prostate-derived PC-3 cells that are CD44- and CD 41 (a2 B1)-positive are enriched in cancer stem cells. This study compared the effect of PC-3...
3.
Anderson K, Jajeh J, Guinan P, Rubenstein M
Anticancer Res . 2009 Dec; 29(11):4579-88. PMID: 20032407
HeLa and PANC-1 cells were exposed to conflicting signals promoting anaerobic or aerobic energy-generating processes and their viability, cell numbers and the ability of HeLa cells to form colonies were...
4.
Anderson K, Jajeh A, Guinan P, Rubenstein M
Med Hypotheses . 2009 Dec; 74(5):868-70. PMID: 20005635
We wonder if the most viable hypoxic cancer stem cells concentrate in more alkaline regions of tumors, favoring their survival and evolution. Alternately, or in addition, do some cancer stem...
5.
Anderson K, Jajeh A, Guinan P, Tsui P, Rubenstein M
Med Hypotheses . 2008 Mar; 70(6):1193-6. PMID: 18364249
We briefly review some implications for therapeutic resistance in solid cancers that could be associated with more alkaline intra-tumor micro-regions reported to exist. Regions of increased alkalinity may provide a...
6.
Anderson K, Darweesh M, Jajah A, Tsui P, Guinan P, Rubenstein M
Anticancer Res . 2007 Aug; 27(4B):2141-53. PMID: 17695497
Reasons for the lodgment of metastases from several types of solid cancer at apparently non-random sites have not been established. Recently, a group of genes expressed in human fibroblasts obtained...
7.
Uziel Y, Gorodnitski N, Mukamel M, Padeh S, Brik R, Barash J, et al.
Lupus . 2007 Apr; 16(2):142-6. PMID: 17402372
The aim of this study was to describe the clinical manifestations and outcomes of a national cohort of childhood systemic lupus erythematosus (cSLE). All cases of cSLE registered in the...
8.
Anderson K, Tsui P, Guinan P, Rubenstein M
Anticancer Res . 2007 Jan; 26(6B):4155-62. PMID: 17201127
Background: Hypoxic cancer cells located beyond the diffusion path of sufficient oxygen are considered a nidus of therapeutic failure. Due to the dependence of many malignantly transformed cells on glycolysis...
9.
Rubenstein M, Tsui P, Guinan P
Methods Find Exp Clin Pharmacol . 2006 Dec; 28(8):515-8. PMID: 17136230
Antisense oligonucleotides (oligos) against transforming growth factor-alpha (TGF-alpha; MR(1)) and its binding site, the epidermal growth factor receptor (EGFR; MR(2)), have proven efficacious against PC-3 and LNCaP prostate tumors when...
10.
Anderson K, Tsui P, Guinan P, Rubenstein M
Med Hypotheses . 2006 Aug; 68(1):166-8. PMID: 16934948
Resistance to various cancer therapies with survival or recurrence of a malignancy has been ascribed to the inability to "kill" hypoxic cancer cells. The reported resistance of cancer "stem" cells...