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» Authors » M R Preetha Rani

M R Preetha Rani

Explore the profile of M R Preetha Rani including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 11
Citations 68
Followers 0
Related Specialties
Biochemistry
Pharmacology
Toxicology
Top 10 Co-Authors
K G Raghu
Anupama Nair
P Salin Raj
Nair Anupama
G L Shyni
K Rajankutty
G Sindhu
Saurav Bhowmick
P M Abdul-Muneer
S Ranjith
Published In
Toxicol In Vitro
Nat Prod Res
Biomed Pharmacother
J Biochem Mol Toxicol
J Neurosci
Affiliations
Soon will be listed here.
Recent Articles
1.
ICAM-1 Deletion Using CRISPR/Cas9 Protects the Brain from Traumatic Brain Injury-Induced Inflammatory Leukocyte Adhesion and Transmigration Cascades by Attenuating the Paxillin/FAK-Dependent Rho GTPase Pathway
Saikia B, Bhowmick S, Malat A, Preetha Rani M, Thaha A, Abdul-Muneer P, et al.
J Neurosci . 2024 Feb; 44(11). PMID: 38326036
Intercellular adhesion molecule-1 (ICAM-1) is identified as an initiator of neuroinflammatory responses that lead to neurodegeneration and cognitive and sensory-motor deficits in several pathophysiological conditions including traumatic brain injury (TBI)....
2.
Discovery of novel microRNAs and their pathogenic responsive target genes in mild traumatic brain injury
Bhowmick S, Preetha Rani M, Singh S, Abdul-Muneer P
Exp Brain Res . 2023 Jul; 241(8):2107-2123. PMID: 37466694
MicroRNAs (miRNAs) are non-coding RNA molecules that function in RNA silencing and post-transcriptional regulation of gene expression. They are profound mediators of molecular and cellular changes in several pathophysiological conditions....
3.
Ferulic acid attenuates high glucose-induced MAM alterations via PACS2/IP3R2/FUNDC1/VDAC1 pathway activating proapoptotic proteins and ameliorates cardiomyopathy in diabetic rats
Salin Raj P, Nair A, Preetha Rani M, Rajankutty K, Ranjith S, Raghu K
Int J Cardiol . 2022 Dec; 372:101-109. PMID: 36481261
Background: Diabetic cardiomyopathy (DCM) is one of the severe complications of diabetes with no known biomarkers for early detection. Mitochondria-associated endoplasmic reticulum membranes (MAM) are less studied subcellular targets but...
4.
Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti-inflammatory, anti-dyslipidemia, and antidiabetic properties
Nair A, Preetha Rani M, Salin Raj P, Ranjit S, Rajankutty K, Raghu K
J Biochem Mol Toxicol . 2022 Sep; 36(12):e23215. PMID: 36117386
Diabetes-related health issues are increasing day by day in public, and diabetic cardiomyopathy (DCM) is one serious issue among them. There is a lack of proper strategy to control and...
5.
In vitro and in vivo studies reveal the beneficial effects of chlorogenic acid against ER stress mediated ER-phagy and associated apoptosis in the heart of diabetic rat
Preetha Rani M, Salin Raj P, Nair A, Ranjith S, Rajankutty K, Raghu K
Chem Biol Interact . 2021 Nov; 351:109755. PMID: 34801538
Endoplasmic reticulum (ER) and associated signaling pathways are involved in diabetic cardiomyopathy (DCM) however, detailed studies are not available. The present study investigated the role of ER stress and related...
6.
Corrigendum to < "Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid"> <[Toxicology in Vitro 53 (2018) 178-192]>
Anupama N, Preetha Rani M, Shyni G, Raghu K
Toxicol In Vitro . 2021 Mar; 72:105020. PMID: 33655884
No abstract available.
7.
Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid
Anupama N, Preetha Rani M, Shyni G, Raghu K
Toxicol In Vitro . 2018 Aug; 53:178-192. PMID: 30144576
Several mechanisms have been proposed for the heart dysfunction during hyperglycemia. The aim of the present in vitro study is to elucidate the role of alterations in redox homeostasis in...
8.
Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status
Preetha Rani M, Anupama N, Sreelekshmi M, Raghu K
Biomed Pharmacother . 2018 Feb; 100:467-477. PMID: 29477910
A series of cardiovascular complications associated with hyperglycemia is a critical threat to the diabetic population. Here we elucidate the link between hyperglycemia and cardiovascular diseases onset, focusing on oxidative...
9.
Insulin resistance in 3T3-L1 adipocytes by TNF-α is improved by punicic acid through upregulation of insulin signalling pathway and endocrine function, and downregulation of proinflammatory cytokines
Anusree S, Sindhu G, Preetha Rani M, Raghu K
Biochimie . 2017 Nov; 146:79-86. PMID: 29180021
Insulin resistance (IR) has become a major threat to public health due to its role in metabolic syndrome. Inflammation associated with IR is an interesting area of biomedical research in...
10.
Bilobalide abates inflammation, insulin resistance and secretion of angiogenic factors induced by hypoxia in 3T3-L1 adipocytes by controlling NF-κB and JNK activation
Priyanka A, Sindhu G, Shyni G, Preetha Rani M, Nisha V, Raghu K
Int Immunopharmacol . 2016 Dec; 42:209-217. PMID: 27936435
Obesity leads to inflammation and insulin resistance in adipose tissue. Hypoxia, observed in obese adipose tissue is suggested as a major cause of inflammation and insulin resistance in obesity. However,...