M R Murthy
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Explore the profile of M R Murthy including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Murthy M, Levesque G, Pandian S, Viallard J, Ogier R, Cavagna A, et al.
Neurochem Int
. 2010 May;
8(3):381-7.
PMID: 20493067
A procedure is described for the preparation of total polysomes, membrane-bound and free polysomes and polysomal mRNA from as little as 5 mg or less of brain tissue. These preparations...
2.
Variability of calcium binding to EF-hand motifs probed by electrospray ionization mass spectrometry
Moorthy A, Singh S, Gopal B, Surolia A, Murthy M
J Am Soc Mass Spectrom
. 2002 Jan;
12(12):1296-301.
PMID: 11766756
The modulation of calcium binding by the EF-hand motifs present in a calmodulin (CAM) homologue, a calcium binding protein (CaBP) from Entamoeba histolytica by three external parameters-pH, ligand coordinator EGTA,...
3.
Moorthy A, Murthy M
J Biomol Struct Dyn
. 2001 Sep;
19(1):47-57.
PMID: 11565851
Calcium plays a key role in cellular signal transduction. Calmodulin, a protein binding four calcium ions, is found in all eukaryotic cells and is believed to activate such processes. The...
4.
Krishna S, Sastri M, Savithri H, Murthy M
J Mol Biol
. 2001 Apr;
307(4):1035-47.
PMID: 11286554
The three-dimensional crystal structure of the empty capsid of Physalis mottle tymovirus has been determined to 3.2 A resolution. The empty capsids crystallized in the space group P1, leading to...
5.
Parthasarathy S, Murthy M
Protein Eng
. 2000 Feb;
13(1):9-13.
PMID: 10679524
The factors contributing to the thermal stability of proteins from thermophilic origins are matters of intense debate and investigation. Thermophilic proteins are thought to possess better packed interiors than their...
6.
Moorthy A, Gopal B, Satish P, Bhattacharya S, Bhattacharya A, Murthy M, et al.
FEBS Lett
. 1999 Nov;
461(1-2):19-24.
PMID: 10561489
The thermodynamics of interaction of two model peptides melittin and mastoparan with bovine brain calmodulin (CAM) and a smaller CAM analogue, a calcium binding protein from Entamoeba histolytica (CaBP) in...
7.
Krishna S, Hiremath C, Munshi S, Prahadeeswaran D, Sastri M, Savithri H, et al.
J Mol Biol
. 1999 Jun;
289(4):919-34.
PMID: 10369772
The structure of the T=3 single stranded RNA tymovirus, physalis mottle virus (PhMV), has been determined to 3.8 A resolution. PhMV crystals belong to the rhombohedral space group R 3,...
8.
Sastri M, Reddy D, Krishna S, Murthy M, Savithri H
J Mol Biol
. 1999 Jun;
289(4):905-18.
PMID: 10369771
Assembly intermediates of icosahedral viruses are usually transient and are difficult to identify. In the present investigation, site-specific and deletion mutants of the coat protein gene of physalis mottle tymovirus...
9.
Velanker S, Gokhale R, Ray S, Gopal B, Parthasarathy S, Santi D, et al.
Protein Sci
. 1999 Apr;
8(4):930-3.
PMID: 10211840
The crystal structure of a covalently cross-linked Lactobacillus casei thymidylate synthase has been determined at 2.8 A resolution. The sites for mutation to achieve the bis-disulfide linked dimer were identified...
10.
Gopal B, Suma R, Murthy M, Bhattacharya A, Bhattacharya S
Acta Crystallogr D Biol Crystallogr
. 1999 Mar;
54(Pt 6 Pt 2):1442-5.
PMID: 10089533
A calcium-binding protein (CaBP) of Entamoeba histolytica was purified from an E. coli recombinant clone carrying the CaBP gene in a pET-3c expression vector using anion-exchange and size-exclusion chromatography. Examination...