M R Jacobson
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Explore the profile of M R Jacobson including associated specialties, affiliations and a list of published articles.
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48
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1643
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Recent Articles
11.
Durham S, Varney V, Gaga M, Jacobson M, Varga E, Frew A, et al.
Clin Exp Allergy
. 1999 Oct;
29(11):1490-6.
PMID: 10520076
Background: Allergen injection immunotherapy is effective for summer hay fever and reduces cutaneous sensitivity to grass pollen. Objective: We have addressed whether this effect of immunotherapy may be due to...
12.
Jacobson M, Juliusson S, Lowhagen O, Balder B, Kay A, Durham S
Clin Exp Allergy
. 1999 Oct;
29(10):1347-55.
PMID: 10520055
Background: Nasal brushing and nasal biopsy are well-tolerated sampling techniques. Seasonal grass pollen-induced rhinitis is characterized by epithelial mast cell infiltration and seasonal increases in both epithelial and sub-mucosal eosinophils....
13.
Durham S, Walker S, Varga E, Jacobson M, OBrien F, Noble W, et al.
N Engl J Med
. 1999 Aug;
341(7):468-75.
PMID: 10441602
Background: Pollen immunotherapy is effective in selected patients with IgE-mediated seasonal allergic rhinitis, although it is questionable whether there is long-term benefit after the discontinuation of treatment. Methods: We conducted...
14.
Varga E, Jacobson M, Till S, Masuyama K, OBrien F, Rak S, et al.
Allergy
. 1999 Jun;
54(4):338-45.
PMID: 10371092
Background: Allergen challenge in allergic rhinitis patients leads to local eosinophilia and Th2-type cytokine expression. Natural exposure to grass pollen is additionally characterized by epithelial mast-cell infiltration. We hypothesized that...
15.
Nouri-Aria K, Masuyama K, Jacobson M, Rak S, Lowhagen O, Schotman E, et al.
Int Arch Allergy Immunol
. 1999 Jan;
117(4):248-54.
PMID: 9876226
Background: Allergen-induced late nasal responses are associated with recruitment of T lymphocytes and eosinophils, and preferential messenger RNA (mRNA) expression of 'TH2-type' cytokines. We previously showed that topical steroid inhibited...
16.
Masuyama K, Till S, Jacobson M, Kamil A, Cameron L, Juliusson S, et al.
J Allergy Clin Immunol
. 1998 Nov;
102(4 Pt 1):610-7.
PMID: 9802369
Background: Nasal allergen provocation in patients with allergic rhinitis leads to expression of the proeosinophilic cytokines IL-5 and GM-CSF and tissue eosinophilia. Objective: We sought to examine the effect of...
17.
Jacobson M, Pederson T
Proc Natl Acad Sci U S A
. 1998 Jul;
95(14):7981-6.
PMID: 9653126
The signal recognition particle (SRP) of eukaryotic cells is a cytoplasmic ribonucleoprotein machine that arrests the translational elongation of nascent secretory and membrane proteins and facilitates their transport into the...
18.
Cameron L, Durham S, Jacobson M, Masuyama K, Juliusson S, Gould H, et al.
J Allergy Clin Immunol
. 1998 Apr;
101(3):330-6.
PMID: 9525448
Background: Nasal allergen provocation has demonstrated that allergen-induced rhinitis is associated with an increase in local IL-4 mRNA and IgE heavy chain (Cepsilon) and IgE heavy chain promoter (Iepsilon) RNA...
19.
Jacobson M, Pederson T
Nucleic Acids Res
. 1998 Mar;
26(3):756-60.
PMID: 9443967
U3 and U8 small nucleolar RNAs (snRNAs) participate in pre-rRNA processing. Like the U1, U2, U4 and U5 major spliceosomal snRNAs, U3 and U8 RNAs are transcribed by RNA polymerase...
20.
Huang Q, Jacobson M, Pederson T
Mol Cell Biol
. 1997 Dec;
17(12):7178-85.
PMID: 9372950
The spliceosomal small nuclear RNAs U1, U2, U4, and U5 are transcribed by RNA polymerase II as precursors with extensions at their 3' ends. The 3' processing of these pre-snRNAs...