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M R Erdos

Explore the profile of M R Erdos including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 820
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Recent Articles
1.
Douglas J, Erdos M, Watanabe R, Braun A, Johnston C, Oeth P, et al.
Diabetes . 2001 Apr; 50(4):886-90. PMID: 11289057
Recent studies have identified a common proline-to-alanine substitution (Pro12Ala) in the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2), a nuclear receptor that regulates adipocyte differentiation and possibly insulin sensitivity. The Pro12Ala variant has...
2.
Ghosh S, Watanabe R, Valle T, Hauser E, Magnuson V, Langefeld C, et al.
Am J Hum Genet . 2000 Oct; 67(5):1174-85. PMID: 11032783
We performed a genome scan at an average resolution of 8 cM in 719 Finnish sib pairs with type 2 diabetes. Our strongest results are for chromosome 20, where we...
3.
Maor S, Abramovitch S, Erdos M, Brody L, Werner H
Mol Genet Metab . 2000 Mar; 69(2):130-6. PMID: 10720440
The insulin-like growth factor I receptor (IGF-I-R) has an important role in breast cancer etiology. The receptor is overexpressed by most breast cancers, where it functions as a potent antiapoptotic...
4.
Marx S, Agarwal S, Kester M, Heppner C, Kim Y, Skarulis M, et al.
Recent Prog Horm Res . 1999 Nov; 54:397-438; discussion 438-9. PMID: 10548885
MEN1 is a syndrome of parathyroid adenomas, gastrinomas, prolactinomas, and other endocrine tumors. Collagenomas and facial angiofibromas are newly recognized but common skin expressions. Many tumors in MEN1 are benign;...
5.
Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos M, et al.
Science . 1999 May; 284(5418):1354-6. PMID: 10334989
Mutations of the breast cancer susceptibility gene BRCA1 confer increased risk for breast, ovarian, and prostatic cancers, but it is not clear why the mutations are associated with these particular...
6.
Ghosh S, Watanabe R, Hauser E, Valle T, Magnuson V, Erdos M, et al.
Proc Natl Acad Sci U S A . 1999 Mar; 96(5):2198-203. PMID: 10051618
We are conducting a genome scan at an average resolution of 10 centimorgans (cM) for type 2 diabetes susceptibility genes in 716 affected sib pairs from 477 Finnish families. To...
7.
Agarwal S, Guru S, Heppner C, Erdos M, Collins R, Park S, et al.
Cell . 1999 Feb; 96(1):143-52. PMID: 9989505
MEN1 is a tumor suppressor gene that encodes a 610 amino acid nuclear protein (menin) of previously unknown function. Using a yeast two-hybrid screen with menin as the bait, we...
8.
Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos M, et al.
Oncogene . 1998 Jul; 16(23):3069-82. PMID: 9662340
In addition to breast and ovarian cancer in women, recent evidence suggests that germ-line mutations of the breast cancer susceptibility gene-1 (BRCA1) also confer an increased life-time risk for prostate...
9.
Hacia J, Makalowski W, Edgemon K, Erdos M, ROBBINS C, Fodor S, et al.
Nat Genet . 1998 Feb; 18(2):155-8. PMID: 9462745
We explored the utility of high-density oligonucleotide arrays (DNA chips) for obtaining sequence information from homologous genes in closely related species. Orthologues of the human BRCA1 exon 11, all approximately...
10.
Humphrey J, Salim A, Erdos M, Collins F, Brody L, Klausner R
Proc Natl Acad Sci U S A . 1997 May; 94(11):5820-5. PMID: 9159158
Germline-inactivating mutations of BRCA1 result in a hereditary predisposition to breast and ovarian cancer. Truncating mutations of BRCA1 predispose to cancer and can be ascertained by protein truncation testing or...