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M Prakash Hande

Explore the profile of M Prakash Hande including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 1718
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Recent Articles
1.
Prathaban K, Hande M
Genome Integr . 2025 Jan; 15():e20240002. PMID: 39845982
Artificial intelligence (AI) offers a broad range of enhancements in medicine. Machine learning and deep learning techniques have shown significant potential in improving diagnosis and treatment outcomes, from assisting clinicians...
2.
Streffer C, Hande M
Int J Radiat Biol . 2024 Aug; 100(9):1237-1239. PMID: 39136525
No abstract available.
3.
Ng G, Loh Z, Fann D, Mallilankaraman K, Arumugam T, Hande M
Genome Integr . 2024 May; 15:e20230003. PMID: 38770527
Physiological processes that govern the normal functioning of mammalian cells are regulated by a myriad of signalling pathways. Mammalian mitogen-activated protein (MAP) kinases constitute one of the major signalling arms...
4.
Sameni S, Viswanathan R, Ng G, Martinez-Lopez W, Hande M
Genome Integr . 2024 May; 14:e20230002. PMID: 38765717
Breast cancer is the most common cause of malignancy and the second most common cause of death due to cancer in women. This heterogeneous disease is currently broadly classified as...
5.
Srikanth P, Chowdhury A, Kah Mun Low G, Saraswathy R, Fujimori A, Banerjee B, et al.
Genome Integr . 2023 Nov; 13:e20220002. PMID: 38021281
Our cellular genome is susceptible to cytotoxic lesions which include single strand breaks and double strand breaks among other lesions. Ataxia telangiectasia mutated (ATM) protein was one of the first...
6.
Krishnan R, Lapierre M, Gautreau B, Nixon K, El Ghamrasni S, Patel P, et al.
Nucleic Acids Res . 2023 Sep; 51(19):10484-10505. PMID: 37697435
Breast cancer linked with BRCA1/2 mutations commonly recur and resist current therapies, including PARP inhibitors. Given the lack of effective targeted therapies for BRCA1-mutant cancers, we sought to identify novel...
7.
Hande M, Nakajima H
Int J Radiat Biol . 2023 Feb; 99(4):712-713. PMID: 36780285
No abstract available.
8.
Kah Mun Low G, Ting A, Fok E, Gopalakrishnan K, Zeegers D, Khaw A, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2022 Apr; 876-877:503444. PMID: 35483790
Xeroderma pigmentosum D (XPD) protein plays a pivotal role in the nucleotide excision repair pathway. XPD unwinds the local area of the damaged DNA by virtue of constituting transcription factor...
9.
Ng G, Hande V, Ong M, Wong B, Loh Z, Ho W, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2022 Apr; 876-877:503472. PMID: 35483787
Telomeres play a critical role in maintaining cellular fate through tight regulation of cell division and DNA damage or repair. Over the years, it is established that biological ageing is...
10.
Rai S, Badarinath A, George A, Sitaraman S, Bronson S, Anandt S, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2022 Feb; 874-875:503439. PMID: 35151422
Telomere shortening has been associated with ageing and with many age-related diseases including cancer, coronary artery disease, heart failure and diabetes. We sought to investigate the link between telomere shortening...