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M Orchinik

Explore the profile of M Orchinik including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 570
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Recent Articles
1.
Breuner C, Orchinik M, Hahn T, Meddle S, Moore I, Owen-Ashley N, et al.
Am J Physiol Regul Integr Comp Physiol . 2003 Jun; 285(3):R594-600. PMID: 12791587
We examined plasticity of the stress response among three populations of the white-crowned sparrow (Zonotrichia leucophrys). These populations breed at different elevations and latitudes and thus have breeding seasons that...
2.
Breuner C, Orchinik M
J Endocrinol . 2002 Oct; 175(1):99-112. PMID: 12379494
Stressors elicit a complex but variable suite of endocrine events. Comparative studies of the stress response have focused primarily on the adrenocortical response to stress, in particular the measurement of...
3.
Deviche P, Breuner C, Orchinik M
Gen Comp Endocrinol . 2001 May; 122(1):67-77. PMID: 11352555
The pharmacology and regulation of corticosteroid binding globulins (CBG) in Dark-eyed Juncos, Junco hyemalis, was investigated. The equilibrium dissociation constant for [(3)H]corticosterone (CORT) binding to plasma was <5 nM. This...
4.
Breuner C, Orchinik M
J Neuroendocrinol . 2001 May; 13(5):412-20. PMID: 11328450
A number of studies have demonstrated seasonal regulation of the adrenocortical response to stress, or of corticosteroid binding globulins, but very few studies have examined seasonal regulation of corticosteroid receptor...
5.
Lowry C, Burke K, Renner K, Moore F, Orchinik M
Horm Behav . 2001 Apr; 39(3):195-205. PMID: 11300710
Monoaminergic systems are important modulators of the neuroendocrine, autonomic, and behavioral responses to stress-related stimuli. The male roughskin newt (Taricha granulosa) was used as a model system to investigate the...
6.
Orchinik M, Carroll S, Li Y, McEwen B, Weiland N
J Neurosci . 2001 Jan; 21(1):330-9. PMID: 11150350
Chronic stressors produce changes in hippocampal neurochemistry, neuronal morphology, and hippocampal-dependent learning and memory processes. In rats, stress-induced changes in CA3 apical dendritic structure are mediated by corticosterone (CORT) acting,...
7.
Jennings D, Moore M, Knapp R, Matthews L, Orchinik M
Gen Comp Endocrinol . 2000 Dec; 120(3):289-99. PMID: 11121294
Plasma steroid-binding globulins, for example, corticosteroid-binding globulin and sex hormone-binding globulin (SHBG), have been identified in a number of vertebrates. One possible function of these proteins is to regulate the...
8.
Breuner C, Jennings D, Moore M, Orchinik M
Gen Comp Endocrinol . 2000 Oct; 120(1):27-34. PMID: 11042008
The potential of mitotane (ortho, para'-DDD, commonly used to treat adrenal carcinomas in humans and dogs) was investigated as an alternative to surgical adrenalectomy in birds, salamanders, and lizards. House...
9.
Orchinik M, Matthews L, Gasser P
Gen Comp Endocrinol . 2000 Jul; 118(2):284-301. PMID: 10890568
To address mechanisms of corticosteroid action, one needs tools for distinguishing between the major classes of corticosteroid binding sites: neuronal membrane-associated receptors, intracellular ligand-activated transcription factors, and corticosteroid binding globulins...
10.
Hastings N, Orchinik M, Aubourg M, McEwen B
Endocrinology . 1999 Sep; 140(10):4459-69. PMID: 10499499
The prairie vole (Microtus ochrogaster) has recently been shown to be glucocorticoid resistant; that is, the prairie vole adrenal axis is refractory to dexamethasone challenge, and highly elevated basal corticosterone...