M Nedergaard
Overview
Explore the profile of M Nedergaard including associated specialties, affiliations and a list of published articles.
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77
Citations
3648
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Recent Articles
1.
Sreetama S, Takano T, Nedergaard M, Simon S, Jaiswal J
Cell Death Differ
. 2015 Oct;
23(4):596-607.
PMID: 26450452
Astrocytes are known to facilitate repair following brain injury; however, little is known about how injured astrocytes repair themselves. Repair of cell membrane injury requires Ca(2+)-triggered vesicle exocytosis. In astrocytes,...
2.
Liu X, Wang C, Fujita T, Malmstrom H, Nedergaard M, Ren Y, et al.
J Dent Res
. 2015 Jul;
94(9):1259-66.
PMID: 26130258
ATP is involved in neurosensory processing, including nociceptive transduction. Thus, ATP signaling may participate in dentin hypersensitivity and dental pain. In this study, we investigated whether pannexins, which can form...
3.
Lundgaard I, Osorio M, Kress B, Sanggaard S, Nedergaard M
Neuroscience
. 2013 Nov;
276:161-73.
PMID: 24231735
Myelination by oligodendrocytes is a highly specialized process that relies on intimate interactions between the axon and the oligodendrocytes. Astrocytes have an important part in facilitating myelination in the CNS,...
4.
Ren Z, Chen X, Yang J, Kress B, Tong J, Liu H, et al.
Neuroscience
. 2013 Mar;
241:89-99.
PMID: 23518227
Spinal cord injury (SCI) initiates a cascade of processes that ultimately form a nonpermissive environment for axonal regeneration. Emerging evidence suggests that regenerative failure may be due in part to...
5.
Rangroo Thrane V, Thrane A, Chang J, Chanag J, Alleluia V, Nagelhus E, et al.
Neuroscience
. 2012 Jun;
220:247-55.
PMID: 22728097
Hepatic encephalopathy (HE) is a potentially fatal complication of acute liver failure, associated with severe neurological dysfunction and coma. The brain's innate immune cells, microglia, have recently been implicated in...
6.
Kang J, Kang N, Yu Y, Zhang J, Petersen N, Tian G, et al.
Neuroscience
. 2010 Jul;
169(4):1601-9.
PMID: 20600669
Sulforhodamine 101 (SR101) has been extensively used for investigation as a specific marker for astroglia in vivo and activity-dependent dye for monitoring regulated exocytosis. Here, we report that SR101 has...
7.
Cotrina M, Lin J, Nedergaard M
Glia
. 2008 Jul;
56(16):1791-8.
PMID: 18649405
Gap junctions are intercellular channels formed by hemichannels (or connexons) from two neighboring cells. Hemichannels, which are composed of proteins called connexins, can function as conduits of ATP and glutamate,...
8.
Simard M, Nedergaard M
Neuroscience
. 2004 Nov;
129(4):877-96.
PMID: 15561405
Astrocytes are highly complex cells that respond to a variety of external stimulations. One of the chief functions of astrocytes is to optimize the interstitial space for synaptic transmission by...
9.
Takano T, Lin J, Arcuino G, Gao Q, Yang J, Nedergaard M
Nat Med
. 2001 Sep;
7(9):1010-5.
PMID: 11533703
Glutamate neurotoxicity has been implicated in stroke, head trauma, multiple sclerosis and neurodegenerative diseases. Although recent data show that cultured glioma cells secrete glutamate, the growth potential of brain tumors...
10.
Jiang L, Xu J, Nedergaard M, Kang J
Neuron
. 2001 Jun;
30(2):503-13.
PMID: 11395010
Brain functions are based on the dynamic interaction of excitatory and inhibitory inputs. Spillover of glutamate from excitatory synapses may diffuse to and modulate nearby inhibitory synapses. By recording unitary...