M N Ehsan
Overview
Explore the profile of M N Ehsan including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
169
Followers
0
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Recent Articles
1.
Bartlett N, Lum B, Fisher G, Brophy N, Ehsan M, Halsey J, et al.
J Clin Oncol
. 1994 Apr;
12(4):835-42.
PMID: 8151326
Purpose: To study the effects of cyclosporine (CsA), a modulator of multidrug resistance (MDR), on the pharmacokinetics and toxicities of doxorubicin. Patients And Methods: Nineteen patients with incurable malignancies entered...
2.
Lum B, Kaubisch S, Yahanda A, Adler K, Jew L, Ehsan M, et al.
J Clin Oncol
. 1992 Oct;
10(10):1635-42.
PMID: 1403041
Purpose: To determine the effects of high-dose cyclosporine (CsA) infusion on the pharmacokinetics of etoposide in patients with cancer. Patients And Methods: Sixteen patients were administered 20 paired courses of...
3.
Marie J, Brophy N, Ehsan M, Aihara Y, Mohamed N, Cornbleet J, et al.
Br J Haematol
. 1992 Jun;
81(2):145-52.
PMID: 1353683
The multidrug resistance gene mdr1, encoding P-glycoprotein (P-gp), can be expressed at high levels in tumour cells derived from normal tissues with constitutive high expression of this gene. In myelogenous...
4.
Lau D, Lewis A, Ehsan M, Sikic B
Cancer Res
. 1991 Oct;
51(19):5181-7.
PMID: 1717140
The cyanomorpholino derivative of doxorubicin (MRA-CN) is a DNA intercalator and alkylator that is a highly potent cytotoxin, non-cross-resistant in multidrug-resistant cells, and noncardiotoxic in comparison with doxorubicin. To further...
5.
Sikic B, Scudder S, Ballon S, Soriero O, Christman J, Suey L, et al.
Semin Oncol
. 1986 Dec;
13(4 Suppl 4):26-32.
PMID: 3099393
The activity of high-dose megestrol acetate was studied in 47 patients with epithelial ovarian cancers after failure of initial chemotherapy. The dose of megestrol acetate was 800 mg/d orally (PO)...
6.
Sikic B, Ehsan M, Harker W, Friend N, BROWN B, Newman R, et al.
Science
. 1985 Jun;
228(4707):1544-6.
PMID: 4012308
The search for new congeners of the leading anticancer drug doxorubicin has led to an analog that is approximately 1000 times more potent, noncardiotoxic at therapeutic dose levels, and non-cross-resistant...