M McDuffie
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Explore the profile of M McDuffie including associated specialties, affiliations and a list of published articles.
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28
Citations
406
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Recent Articles
1.
Ernst P, Erickson L, Loo W, SCOTT K, Wiznerowicz E, Brown C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2011 Sep;
302(1):G105-15.
PMID: 21921286
SAMP1/YitFcs mice serve as a model of Crohn's disease, and we have used them to assess gastritis. Gastritis was compared in SAMP1/YitFcs, AKR, and C57BL/6 mice by histology, immunohistochemistry, and...
2.
Seydel F, Garrigan E, Stutevoss B, Belkin N, Makadia B, Carter J, et al.
J Autoimmun
. 2008 Oct;
31(4):377-84.
PMID: 18945591
Myeloid cells from non-obese diabetic (NOD) mouse and human type 1 diabetic (T1D) patients overexpress granulocyte-macrophage colony stimulation factor (GM-CSF). This overproduction prolongs the activation of signal transduction and activator...
3.
Hamano S, Becker S, Asgharpour A, Ocasio Y, Stroup S, McDuffie M, et al.
Genes Immun
. 2008 May;
9(5):452-61.
PMID: 18480826
Resistance to the establishment of intestinal Entamoeba histolytica infection is dependent on the inbred mouse strain. In this work we used the inbred strains B6 (resistant), CBA (susceptible), B6CBAF(1) and...
4.
Khromov A, Wang H, Choudhury N, McDuffie M, Herring B, Nakamoto R, et al.
Proc Natl Acad Sci U S A
. 2006 Feb;
103(7):2440-5.
PMID: 16461919
Cyclic nucleotides can relax smooth muscle without a change in [Ca2+]i, a phenomenon termed Ca2+ desensitization, contributing to vasodilation, gastrointestinal motility, and airway resistance. The physiological importance of telokin, a...
5.
Pearson-White S, McDuffie M
Mol Cell Biol
. 2003 Jul;
23(15):5446-59.
PMID: 12861029
The proto-oncogene Sno has been shown to be a negative regulator of transforming growth factor beta (TGF-beta) signaling in vitro, using overexpression and artificial reporter systems. To examine Sno function...
6.
Yang Z, Chen M, Wu R, McDuffie M
Diabetologia
. 2002 Sep;
45(9):1307-14.
PMID: 12242464
Aims/hypothesis: Pro-inflammatory cytokines are increased during the active stages of Type I (insulin-dependent) diabetes mellitus. The aim of this study was to investigate the applicability of using a new anti-inflammatory...
7.
Waters S, Fu S, Gaskin F, Deshmukh U, Sung S, Kannapell C, et al.
Clin Immunol
. 2001 Aug;
100(3):372-83.
PMID: 11513551
Among NZB/W-derived New Zealand mixed (NZM) strains, only NZM/Aeg2410 (NZM2410) has been well characterized. In contrast to NZM2410, NZM2328 mice develop autoantibodies and acute and severe chronic glomerulonephritis (GN) with...
8.
McDuffie M
Clin Immunol
. 2000 Jul;
96(2):119-30.
PMID: 10900159
Autoimmune diabetes is a polygenic disease process in man and rodents. To identify and characterize genes involved in the pathogenesis of diabetes in nonobese diabetic (NOD) mice, we initiated a...
9.
McDuffie M
Curr Opin Immunol
. 1999 Jan;
10(6):704-9.
PMID: 9914220
Type I diabetes has resisted direct genetic analysis in humans but two excellent models of disease in rodents provide a more readily manipulated alternative for study. These rodent models are...
10.
McDuffie M, Haskins K
Proc Natl Acad Sci U S A
. 1995 Feb;
92(5):1386-90.
PMID: 7877988
Identification of diabetes-associated T-cell autoantigens is important for understanding the immunopathology of diabetes and developing improved therapeutic strategies. We have used a genetic approach to move toward identifying the autoantigen...