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M Mayford

Explore the profile of M Mayford including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Glazewski S, Bejar R, Mayford M, Fox K
Neuropharmacology . 2001 Oct; 41(6):771-8. PMID: 11640932
The calcium/calmodulin kinase II (CaMKII) autophosphorylation site is thought to be important for plasticity, learning and memory. If autophosphorylation is prevented by a point mutation (T286A) LTP is blocked in...
2.
Krestel H, Mayford M, Seeburg P, Sprengel R
Nucleic Acids Res . 2001 Mar; 29(7):E39. PMID: 11266574
Doxycycline (Dox)-sensitive co-regulation of two transcriptionally coupled transgenes was investigated in the mouse. For this, we generated four independent mouse lines carrying coding regions for green fluorescent protein (GFP) and...
3.
Lumsden A, Chapman S, Schubert F, Toole L, Mayford M, Hamann S, et al.
Curr Opin Neurobiol . 2001 Feb; 11(1):1-9. PMID: 11179863
No abstract available.
4.
Sandberg R, Yasuda R, Pankratz D, Carter T, Del Rio J, Wodicka L, et al.
Proc Natl Acad Sci U S A . 2000 Sep; 97(20):11038-43. PMID: 11005875
To determine the genetic causes and molecular mechanisms responsible for neurobehavioral differences in mice, we used highly parallel gene expression profiling to detect genes that are differentially expressed between the...
5.
Wiedenmayer C, Myers M, Mayford M, Barr G
Neuroreport . 2000 May; 11(5):1051-5. PMID: 10790881
Spatial learning and memory involves the ability to encode geometric relationships between perceived cues and depends critically on the hippocampus. Visually guided spatial learning has been demonstrated in adult animals....
6.
Mayford M, Kandel E
Trends Genet . 1999 Oct; 15(11):463-70. PMID: 10529810
The ability to remember is perhaps the most significant and distinctive feature of our mental life. We are who we are largely because of what we have learned and what...
7.
Miller S, Mayford M
Curr Opin Genet Dev . 1999 Jun; 9(3):333-7. PMID: 10377283
Studies of the cellular and molecular mechanisms of memory formation have focused on the role of long-lasting forms of synaptic plasticity such as long-term potentiation (LTP). A combination of genetic,...
8.
Mansuy I, Winder D, Moallem T, Osman M, Mayford M, Hawkins R, et al.
Neuron . 1998 Sep; 21(2):257-65. PMID: 9728905
To obtain rapidly inducible and reversible expression of transgenes in the forebrain of the mouse, we have combined the reverse tetracycline-controlled transactivator (rtTA) system with the CaMKIIalpha promoter. We show...
9.
Mansuy I, Mayford M, Jacob B, Kandel E, Bach M
Cell . 1998 Mar; 92(1):39-49. PMID: 9489698
To investigate the roles phosphatases play in hippocampal-dependent memory, we studied transgenic mice overexpressing a truncated form of calcineurin. These mice have normal short-term memory but defective long-term memory evident...
10.
Mayford M, Mansuy I, Muller R, Kandel E
Curr Biol . 1997 Sep; 7(9):R580-9. PMID: 9285710
The use of standard genetic techniques, such as gene targeting and transgenesis, to study cognitive function in adult animals suffers from the limitations that the gene under study is often...