M M J Kool
Overview
Explore the profile of M M J Kool including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
42
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0
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Recent Articles
1.
Kool M, Galac S, van der Helm N, Corradini S, Kooistra H, Mol J
J Vet Intern Med
. 2015 Jan;
29(1):214-24.
PMID: 25619516
Background: Hypercortisolism is a common endocrine disorder in dogs, caused by a cortisol-secreting adrenocortical tumor (AT) in approximately 15% of cases. In adrenocortical carcinomas of humans, activation of the phosphatidylinositol...
2.
Campos M, Kool M, Daminet S, Ducatelle R, Rutteman G, Kooistra H, et al.
J Vet Intern Med
. 2014 Sep;
28(6):1814-23.
PMID: 25231196
Background: Information on the genetic events leading to thyroid cancer in dogs is lacking. Hypothesis/objectives: Upregulation of the PI3K/Akt pathway has an important role in the tumorigenesis of thyroid carcinoma...
3.
Galac S, Kool M, van den Berg M, Mol J, Kooistra H
Domest Anim Endocrinol
. 2014 Jul;
49:1-5.
PMID: 25010021
We report on a screening for the relative messenger RNA (mRNA) and protein expression of steroidogenic factor 1 (SF-1) in normal canine adrenals (n = 10) and cortisol-secreting adrenocortical tumors...
4.
Kool M, Galac S, Kooistra H, Mol J
Domest Anim Endocrinol
. 2014 Jan;
47:73-82.
PMID: 24377872
The aim of this study was to evaluate the expression of angiogenesis-related genes in canine cortisol-secreting adrenocortical tumors (ATs). Quantitative RT-PCR analysis revealed mRNA encoding for vascular endothelial growth factor,...
5.
Kool M, Galac S, Spandauw C, Kooistra H, Mol J
J Vet Intern Med
. 2013 Oct;
27(6):1486-92.
PMID: 24112376
Background: Cushing's syndrome or hypercortisolism is a common endocrinopathy in dogs. In approximately 15% of cases, the disorder is caused by adrenocorticotropin (ACTH)-independent hypersecretion of cortisol by an adrenocortical tumor...
6.
Galac S, Kool M, Naan E, Daminet S, Mol J, Kooistra H
Domest Anim Endocrinol
. 2010 Oct;
39(4):259-67.
PMID: 20920783
Studies of human adrenocortical tumors (ATs) causing Cushing's syndrome suggest that hypersecretion of cortisol is caused by altered expression of steroidogenic enzymes and that steroidogenesis can only be maintained when...