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M M Hardee

Explore the profile of M M Hardee including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 39
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Recent Articles
1.
Dunn C, Hardee M, Fidler S, Shields S, Chosay J
J Leukoc Biol . 1996 Jul; 60(1):27-36. PMID: 8699120
Subcutaneous injection of recombinant human interleukin-2 (rhuIL-2) at 10(2)-10(4) U/mouse induced delayed (48 h) accumulation of mononuclear leukocytes with diffuse granulocytes, including eosinophils. Subcutaneous local infusion of rhuIL-2 or recombinant...
2.
Trim C, Moore J, Hardee M, Hardee G, Slade E
Res Vet Sci . 1991 Jan; 50(1):54-63. PMID: 2047592
Horses with colic may be endotoxaemic and subsequently develop hypotension during anaesthesia for surgical operation. The aim of this study was to evaluate the efficacy of dopamine as a means...
3.
Dunn C, Hardee M, Staite N
Agents Actions . 1989 Jun; 27(3-4):290-3. PMID: 2508441
The contention that cytokines are important mediators of inflammation prompted the present studies which were designed to compare acute and chronic pathological effects of locally-administered recombinant (r) IL-1 alpha, IL-1...
4.
Dunn C, Hardee M, Gibbons A, Staite N, RICHARD K
Clin Sci (Lond) . 1989 Mar; 76(3):261-3. PMID: 2494015
1. The present study describes the pathological responses to local administration of recombinant cytokines in subcutaneously implanted slow-release ethylene vinyl acetate (EVA) co-polymer in mice. 2. EVA-recombinant human interleukin-1 beta...
5.
Dunn C, Staite N, Hardee M
Ann Intern Med . 1988 Nov; 109(9):761-2. PMID: 3263824
No abstract available.
6.
Tracey D, Hardee M, RICHARD K, Paslay J
Immunopharmacology . 1988 Jan; 15(1):47-62. PMID: 3258857
The effects of a panel of hormones and pharmacological agents on the activation of T cells by a combination of interleukin-1 and phytohemagglutinin (IL-1/PHA) was studied. Pharmacological effects on various...
7.
Semrad S, Hardee G, Hardee M, Moore J
Equine Vet J . 1987 May; 19(3):201-6. PMID: 3608957
The efficacy of low doses of flunixin meglumine in reducing eicosanoid generation and clinical signs in response to experimentally induced endotoxaemia was investigated. Thromboxane B2 and 6-keto-prostaglandin F1 alpha were...
8.
Hardee M, Moore J, Hardee G
Res Vet Sci . 1986 Mar; 40(2):152-6. PMID: 3517992
The efficacy of three agents which alter the metabolism of arachidonic acid was investigated in normal, conscious horses. A dose response evaluation was made of flunixin meglumine and phenylbutazone, two...
9.
Moore J, Hardee M, Hardee G
Am J Vet Res . 1986 Jan; 47(1):110-3. PMID: 3080926
Two cyclooxygenase inhibitors (flunixin meglumine and phenylbutazone) and a selective thromboxane synthetase inhibitor were assessed in the management of experimental equine endotoxemia. Drugs or saline solution were administered to 16...
10.
Semrad S, Hardee G, Hardee M, Moore J
Am J Vet Res . 1985 Dec; 46(12):2474-9. PMID: 4083579
The pharmacokinetics and inhibition of prostaglandin synthesis in conscious horses given various dosages of flunixin meglumine were studied. Plasma concentrations of flunixin were measured by high-performance liquid chromatography, and serum...