M L Read
Overview
Explore the profile of M L Read including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
350
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Recent Articles
1.
Imruetaicharoenchoke W, Fletcher A, Lu W, Watkins R, Modasia B, Poole V, et al.
Endocr Relat Cancer
. 2017 Jul;
24(9):459-474.
PMID: 28676500
Pituitary tumor-transforming gene 1-binding factor (PTTG1IP; PBF) is a multifunctional glycoprotein, which is overexpressed in a wide range of tumours, and significantly associated with poorer oncological outcomes, such as early...
2.
Read M, Fong J, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson R, et al.
Oncogene
. 2017 May;
36(37):5296-5308.
PMID: 28504713
The proto-oncogene PTTG and its binding partner PBF have been widely studied in multiple cancer types, particularly thyroid and colorectal, but their combined role in tumourigenesis is uncharacterised. Here, we...
3.
Smith V, Sharma N, Watkins R, Read M, Ryan G, Kwan P, et al.
J Clin Endocrinol Metab
. 2013 May;
98(7):2876-86.
PMID: 23678037
Context: The clinical effectiveness of ablative radioiodine treatment of thyroid tumors is limited by the availability of the sodium iodide symporter (NIS) at the plasma membrane (PM) for uptake of...
4.
Smith V, Read M, Turnell A, Sharma N, Lewy G, Fong J, et al.
Endocrinology
. 2012 Apr;
153(7):3526-36.
PMID: 22535767
Within the basolateral membrane of thyroid follicular epithelial cells, two transporter proteins are central to thyroid hormone (TH) biosynthesis and secretion. The sodium iodide symporter (NIS) delivers iodide from the...
5.
Read M, Bettinger T, Oupicky D
Methods Mol Med
. 2011 Feb;
65:131-48.
PMID: 21318751
There is an urgent requirement in the field of gene therapy for gene transfer vectors that are both safe to use and able to efficiently deliver therapeutic genes to target...
6.
Oupicky D, Read M, Bettinger T
Methods Mol Med
. 2011 Feb;
65:61-78.
PMID: 21318745
Polycation-DNA complexes represent promising synthetic vectors for gene delivery, showing good transfection activities in vitro and safety in vivo. However, simple polycation-DNA complexes suffer from several disadvantages that limit their...
7.
Kim D, Fong J, Read M, McCabe C
Mol Cell Endocrinol
. 2007 Oct;
278(1-2):1-6.
PMID: 17928133
It is now 10 years since PTTG was first cloned and isolated. Perhaps the major story of the intervening decade of work performed by numerous groups around the world is...
8.
Barrett L, Berry M, Ying W, Hodgkin M, Seymour L, Gonzalez A, et al.
J Gene Med
. 2004 Apr;
6(4):429-38.
PMID: 15079817
Background: Efficient neuronal gene therapy is a goal for the long-term repair and regeneration of the injured central nervous system (CNS). We investigated whether targeting cDNA to neurons with cholera...
9.
Bettinger T, Carlisle R, Read M, Ogris M, Seymour L
Nucleic Acids Res
. 2001 Sep;
29(18):3882-91.
PMID: 11557821
Synthetic vectors were evaluated for their ability to mediate efficient mRNA transfection. Initial results indicated that lipoplexes, but not polyplexes based on polyethylenimine (PEI, 25 and 22 kDa), poly(L-lysine) (PLL,...
10.
Bettinger T, Read M
Curr Opin Mol Ther
. 2001 May;
3(2):116-24.
PMID: 11338923
The introduction of RNA into mammalian cells is a relatively straightforward procedure with many therapeutic applications. An advantage of using mRNA is that protein expression can be achieved in post-mitotic...