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M L Menot

Explore the profile of M L Menot including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
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Recent Articles
1.
Perez B, Mechinaud F, Galambrun C, Ben Romdhane N, Isidor B, Philip N, et al.
J Med Genet . 2010 Jun; 47(10):686-91. PMID: 20543203
Background: CBL missense mutations have recently been associated with juvenile myelomonocytic leukaemia (JMML), an aggressive myeloproliferative and myelodysplastic neoplasm of early childhood characterised by excessive macrophage/monocyte proliferation. CBL, an E3...
2.
Cassinat B, Bellanne-Chantelot C, Notz-Carrere A, Menot M, Vaury C, Micheau M, et al.
Leukemia . 2004 Jul; 18(9):1553-5. PMID: 15284863
No abstract available.
3.
Da Silva N, Meyer-Monard S, Menot M, Parrado A, Lebel A, Balitrand N, et al.
Hematol J . 2002 Mar; 1(5):316-28. PMID: 11920209
Introduction: Efficacy of differentiating agents requires that their specific cellular targets are still expressed and functional in the leukemic cells. One hypothesis to target sensitive cells is to select leukemic...
4.
Cassinat B, Chevret S, Zassadowski F, Balitrand N, Guillemot I, Menot M, et al.
Blood . 2001 Oct; 98(9):2862-4. PMID: 11675363
Acute promyelocytic leukemia (APL) blasts possess a unique sensitivity to the differentiating effects of all-trans retinoic acid (ATRA). Multicenter trials confirm that the combination of differentiation and cytotoxic therapy prolongs...
5.
Cambier N, Menot M, Schlageter M, Balitrand N, Leblanc T, Bordigoni P, et al.
Hematol J . 2001 Jun; 2(2):97-102. PMID: 11424001
Introduction: All trans retinoic acid, the active metabolite of vitamin A, exerts profound effects on cell differentiation. On normal myeloid progenitors, retinoids switch the differentiation program of granulo-macrophagic progenitors towards...
6.
Da Silva N, Meyer-Monard S, Menot M, Degos L, Baruchel A, Dombret H, et al.
Cytokines Cell Mol Ther . 1997 Jun; 3(2):75-80. PMID: 9287246
In an attempt to find new agents that promote differentiation and have therapeutic potential in acute myeloid leukemias, we have studied the effect of recombinant human granulocyte colony stimulating factor...
7.
Cambier N, Baruchel A, Schlageter M, Menot M, Wattel E, Fenaux P, et al.
Hematol Cell Ther . 1997 Apr; 39(2):41-8. PMID: 9168299
Chronic myelomonocytic leukemia represents a distinct myelodysplastic syndrome in which an excess of monocytes is observed both in the blood and bone marrow of the patients. Whereas diagnosis is relatively...
8.
Cambier N, Wattel E, Menot M, Guerci A, Chomienne C, Fenaux P
Leukemia . 1996 Jul; 10(7):1164-7. PMID: 8683997
Retinoids can inhibit the spontaneous in vitro growth of CFU-GM observed in juvenile chronic myeloid leukemia (JCML) and, when administered in vivo, have shown some clinical benefit in this disease....
9.
Agadir A, Cornic M, Jerome M, Menot M, Cambier N, Gaub M, et al.
Biochem Biophys Res Commun . 1995 Aug; 213(1):112-22. PMID: 7639724
The diverse effects of all-trans retinoic acid (ATRA) on growth, differentiation and homeostasis of vertebrate organisms are mediated by three distinct isoforms of retinoic acid receptors (RARs). Although it is...
10.
Gratas C, Menot M, Dresch C, Chomienne C
Leukemia . 1993 Aug; 7(8):1156-62. PMID: 8350615
In the new context of the use of retinoic acid (RA) therapy as an inducer of leukemic differentiation and a selective inhibitor of human myeloid leukemia cell growth, we undertook...