M Komrakova
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Explore the profile of M Komrakova including associated specialties, affiliations and a list of published articles.
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14
Citations
92
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Recent Articles
1.
Roch P, Noisser L, Boker K, Hoffmann D, Schilling A, Sehmisch S, et al.
J Endocrinol Invest
. 2023 Sep;
47(3):709-720.
PMID: 37672168
Purpose: Selective androgen (ostarine, OST) and estrogen (raloxifene, RAL) receptor modulators with improved tissue selectivity have been developed as alternatives to hormone replacement therapy. We investigated the combined effects of...
2.
Boker K, Komrakova M, Fahrendorff L, Spelsberg B, Hoffmann D, Schilling A, et al.
Endocrine
. 2023 Jun;
81(3):579-591.
PMID: 37378829
Purpose: The selective androgen receptor modulator ostarine has been shown to have advantageous effects on skeletal tissue properties, reducing muscle wasting and improving physical function in males. However, data on...
3.
Komrakova M, Buchler G, Boker K, Lehmann W, Schilling A, Roch P, et al.
J Endocrinol Invest
. 2022 Jul;
45(12):2299-2311.
PMID: 35867330
Purpose: Enobosarm (EN), a selective androgen receptor modulator and raloxifene (RAL), a selective estrogen receptor modulator, have been shown to improve bone tissue in osteoporotic males. The present study evaluated...
4.
Roch P, Wolgast V, Gebhardt M, Boker K, Hoffmann D, Saul D, et al.
J Endocrinol Invest
. 2022 Apr;
45(8):1555-1568.
PMID: 35429299
Purpose: Selective androgen and estrogen receptor modulators, ostarine (OST) and raloxifen (RAL), reportedly improve muscle tissue and offer therapeutic approaches to muscle maintenance in the elderly. The present study evaluated...
5.
Komrakova M, Rechholtz C, Pohlmann N, Lehmann W, Schilling A, Wigger R, et al.
Bone Rep
. 2019 Sep;
11:100224.
PMID: 31516917
Bisphosphonate alendronate (ALN), phytoestrogen 8-prenylnaringenin (8-PN) and the whole body vibration exert a favorable effect on osteoporotic bone. However, the impact of these treatments and the combination of pharmacological therapies...
6.
Hoffmann D, Komrakova M, Pflug S, von Oertzen M, Saul D, Weiser L, et al.
J Bone Miner Metab
. 2018 May;
37(2):243-255.
PMID: 29785666
Selective androgen receptor modulators (SARMs) have shown beneficial effects on muscle wasting, general physical function and bone properties in male mammals. However, data on the effects of SARMs in postmenopausal...
7.
Komrakova M, Fiebig J, Hoffmann D, Krischek C, Lehmann W, Stuermer K, et al.
Calcif Tissue Int
. 2018 Jan;
103(1):80-94.
PMID: 29352329
Most models of osteoporotic bone fractures are performed unilaterally (UL). We investigated healing of tibia osteotomy performed either UL or bilaterally (BL) in ovariectomized rats. Behavior of animals and muscle...
8.
Saul D, Harlas B, Ahrabi A, Kosinsky R, Hoffmann D, Wassmann M, et al.
Calcif Tissue Int
. 2017 Dec;
102(6):705-719.
PMID: 29242963
Osteoporosis is often accompanied by sarcopenia. The effect of strontium ranelate (SR) on muscle tissue has not been investigated sufficiently. In this study, the effect of different SR treatments on...
9.
Effect of zileuton on osteoporotic bone and its healing, expression of bone, and brain genes in rats
Saul D, Ninkovic M, Komrakova M, Wolff L, Simka P, Gasimov T, et al.
J Appl Physiol (1985)
. 2017 Sep;
124(1):118-130.
PMID: 28860177
Estrogen deficiency and aging are associated with osteoporosis, impaired bone healing, and lower cognitive performance. Close functional and physical connections occur between bone and the central nervous system. An anti-inflammatory...
10.
Saul D, Gleitz S, Nguyen H, Kosinsky R, Sehmisch S, Hoffmann D, et al.
Bone
. 2017 Apr;
101:134-144.
PMID: 28455215
Osteoporosis is one of the most common diseases worldwide. In osteoporosis, vertebral fractures represent a major burden. Lipoxygenase (LOX) inhibitors such as baicalein and zileuton may represent a promising therapeutic...