M James Phillips
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Explore the profile of M James Phillips including associated specialties, affiliations and a list of published articles.
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33
Citations
930
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Recent Articles
1.
Bodewes F, van der Wulp M, Beharry S, Doktorova M, Havinga R, Boverhof R, et al.
J Cyst Fibros
. 2015 Jan;
14(4):440-6.
PMID: 25633479
Background: Cftr(-/-tm1Unc) mice develop progressive hepato-biliary pathology. We hypothesize that this liver pathology is related to alterations in biliary bile hydrophobicity and bile salt metabolism in Cftr(-/-tm1Unc) mice. Methods: We...
2.
Urbanellis P, Shyu W, Khattar R, Wang J, Zakharova A, He W, et al.
Immunology
. 2014 Jul;
144(1):91-106.
PMID: 24990517
Therapies that promote tolerance in solid organ transplantation will improve patient outcomes by eliminating the need for long-term immunosuppression. To investigate mechanisms of rapamycin-induced tolerance, C3H/HeJ mice were heterotopically transplanted...
3.
Khattar R, Luft O, Yavorska N, Shalev I, James Phillips M, Adeyi O, et al.
PLoS One
. 2013 Oct;
8(10):e72309.
PMID: 24146739
Mounting effective innate and adaptive immune responses are critical for viral clearance and the generation of long lasting immunity. It is known that production of inhibitory factors may result in...
4.
Liu H, Yang P, Zhu T, Manuel J, Zhang J, He W, et al.
Int J Biochem Cell Biol
. 2012 Nov;
45(2):408-18.
PMID: 23127799
Fibrinogen-like protein 2 (FGL2), a novel effector molecule of CD4(+)CD25(+)Foxp3(+) regulatory T cells (Treg), mediates its suppressive activity through binding to low affinity Fcγ receptors expressed on antigen presenting cells...
5.
Chang K, Chadha N, Leung R, Shago M, James Phillips M, Thorner P
Pediatr Dev Pathol
. 2009 Dec;
13(4):331-7.
PMID: 20021220
Lymphadenoma of the salivary gland is a rare benign tumor with only 11 reported cases in the English language literature, most of which have occurred in adults. We report a...
6.
Bartlett J, Friedman K, Ling S, Pace R, Bell S, Bourke B, et al.
JAMA
. 2009 Sep;
302(10):1076-83.
PMID: 19738092
Context: A subset (approximately 3%-5%) of patients with cystic fibrosis (CF) develops severe liver disease with portal hypertension. Objective: To assess whether any of 9 polymorphisms in 5 candidate genes...
7.
Wang R, Chen H, Liu L, Sheps J, James Phillips M, Ling V
Hepatology
. 2009 Aug;
50(3):948-56.
PMID: 19650158
Unlabelled: Bile salt export pump (BSEP; ATP-binding cassette, subfamily B, member 11) mutations in humans result in progressive familial intrahepatic cholestasis type 2, a fatal liver disease with greatly reduced...
8.
Shalev I, Wong K, Foerster K, Zhu Y, Chan C, Maknojia A, et al.
Hepatology
. 2008 Dec;
49(2):387-97.
PMID: 19085958
Unlabelled: Fulminant viral hepatitis (FH) remains an important clinical problem in which the underlying pathogenesis is not well understood. Here, we present insight into the immunological mechanisms involved in FH...
9.
Shalev I, Liu H, Koscik C, Bartczak A, Javadi M, Wong K, et al.
J Immunol
. 2007 Dec;
180(1):249-60.
PMID: 18097026
Mice with targeted deletion of fibrinogen-like protein 2 (fgl2) spontaneously developed autoimmune glomerulonephritis with increasing age, as did wild-type recipients reconstituted with fgl2-/- bone marrow. These data implicate FGL2 as...
10.
Watanabe N, Kojima S, Takashimizu S, Nishizaki Y, Kagawa T, James Phillips M
J Gastroenterol Hepatol
. 2007 Oct;
22(11):1983-92.
PMID: 17914981
Background And Aim: The precise mechanism of bile regurgitation from the biliary system to the blood stream still remains to be elucidated. The aim of this study was to examine...