M J Kluger
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Explore the profile of M J Kluger including associated specialties, affiliations and a list of published articles.
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146
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2105
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Recent Articles
1.
Henderson R, Barr E, Blackwell W, Clark C, Conn C, Kalra R, et al.
Toxicol Ind Health
. 2003 Jan;
17(5-10):294-7.
PMID: 12539875
Subclinical, repeated exposures of F344 rats to sarin resulted in brain alterations in densities of chlonergic receptor subtypes that may be associated with memory loss and cognitive dysfunction. The exposures...
2.
Gourine A, Rudolph K, Korsak A, Kubatko J, Tesfaigzi J, Kozak W, et al.
Neuroimmunomodulation
. 2001 Jul;
9(1):13-22.
PMID: 11435748
Objective: Peripheral afferents play an important role in fever. In the present study, we investigated the role of capsaicin-sensitive afferents in fever and cytokine responses during systemic (induced by intraperitoneal...
3.
Kozak W, Kluger M, Tesfaigzi J, Kozak A, Mayfield K, Wachulec M, et al.
Ann N Y Acad Sci
. 2001 Mar;
917:121-34.
PMID: 11268336
This review summarizes recent studies on endogenous antipyretic mechanisms. Fever is the result of a balance between pyrogenic and cryogenic cytokines and hormones. Although there is considerable evidence that fever...
4.
Dokladny K, Kozak A, Wachulec M, Wallen E, Menache M, Kozak W, et al.
Am J Physiol Regul Integr Comp Physiol
. 2001 Feb;
280(2):R338-44.
PMID: 11208560
We have previously reported that heat conditioning augments lipopolysaccharide (LPS)-induced fever in rats, which is accompanied by an accumulation of heat shock protein (HSP) in the liver and the reduction...
5.
Frank S, Kluger M, Kunkel S
Anesthesiology
. 2001 Jan;
93(6):1426-31.
PMID: 11149437
Background: The mechanism and clinical relevance of increased core temperature (Tc) after surgery are poorly understood. Because fever is used as a diagnostic sign of infection, it is important to...
6.
Kozak W, Kluger M, Kozak A, Wachulec M, Dokladny K
Am J Physiol Regul Integr Comp Physiol
. 2000 Aug;
279(2):R455-60.
PMID: 10938232
In previous reports, we (15, 18) and others (29) demonstrated data showing that various inhibitors of cytochrome P-450/epoxygenase augment fever in rats and mice, indicating that the enzyme may be...
7.
Gourine A, Rudolph K, Leon L, Kluger M
Neuroimmunomodulation
. 2000 Jun;
8(1):8-12.
PMID: 10859482
Interleukin (IL)-11 is a member of the gp130 family of cytokines. In contrast to IL-6 (another gp130 cytokine), IL-11 does not induce fever in humans. In the present study, the...
8.
Mayfield K, Soszynski D, Kozak W, Kozak A, Rudolph K, Kluger M
Neuroimmunomodulation
. 1999 Jul;
6(4):305-17.
PMID: 10393517
Exposure to psychological stress increases body temperature (Tb). This stress fever may be immunologically beneficial in some patient populations but detrimental in others (e.g., HIV-infected individuals). For this reason, it...
9.
Leon L, Kozak W, Rudolph K, Kluger M
Am J Physiol
. 1999 Jan;
276(1):R81-9.
PMID: 9887180
Interleukin (IL)-10 inhibits the synthesis of proinflammatory cytokines implicated in fever, including IL-1beta, IL-6, and tumor necrosis factor (TNF)-alpha. We hypothesized that IL-10 functions as an antipyretic in the regulation...
10.
Kozak W, Archuleta I, Mayfield K, Kozak A, Rudolph K, Kluger M
Am J Physiol
. 1998 Oct;
275(4):R1031-40.
PMID: 9756531
Inhibitors of cyclooxygenases prevent fever. The purpose of this study was to test the hypothesis that selective and dual inhibitors of the other enzyme systems of arachidonic acid oxygenation (i.e.,...