M Hurme
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Explore the profile of M Hurme including associated specialties, affiliations and a list of published articles.
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251
Citations
3296
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Recent Articles
1.
Kananen L, Enroth L, Raitanen J, Jylhava J, Burkle A, Moreno-Villanueva M, et al.
Sci Rep
. 2021 Mar;
11(1):6139.
PMID: 33731775
Self-rated health (SRH) is one of the most frequently used indicators in health and social research. Its robust association with mortality in very different populations implies that it is a...
2.
Kananen L, Hurme M, Jylha M, Harkanen T, Koskinen S, Stenholm S, et al.
Sci Rep
. 2020 Aug;
10(1):13809.
PMID: 32796872
Increased levels of circulating cell-free DNA (cf-DNA) are associated with and predict poor health outcomes. However, its predictive ability for mortality in population-based samples remains understudied. We analysed the capability...
3.
Ozsait-Selcuk B, Komurcu-Bayrak E, Jylha M, Luukkaala T, Perola M, Kristiansson K, et al.
Ann Hum Genet
. 2018 Sep;
83(1):34-45.
PMID: 30203836
Upstream transcription factor 1 (USF1) regulates the transcription of many genes related to cell and organism survival processes such as stress and immune response, regulation of cellular senesce, and carcinogenesis....
4.
Rannikko J, Seiskari T, Huttunen R, Tarkiainen I, Jylhava J, Hurme M, et al.
J Intern Med
. 2018 Apr;
284(4):418-426.
PMID: 29687943
Background: A few studies have shown that both quick Sequential Organ Failure Assessment (qSOFA) score and cell-free DNA (cfDNA) have potential use as a prognostic marker in patients with infection....
5.
Karlsson Linner R, Marioni R, Rietveld C, Simpkin A, Davies N, Watanabe K, et al.
Mol Psychiatry
. 2017 Nov;
22(12):1680-1690.
PMID: 29086770
The epigenome is associated with biological factors, such as disease status, and environmental factors, such as smoking, alcohol consumption and body mass index. Although there is a widespread perception that...
6.
Kananen L, Marttila S, Nevalainen T, Kummola L, Junttila I, Mononen N, et al.
Age (Dordr)
. 2016 Jun;
38(3):65.
PMID: 27300324
The epigenetic clock, defined as the DNA methylome age (DNAmAge), is a candidate biomarker of ageing. In this study, we aimed to characterize the behaviour of this marker during the...
7.
Kananen L, Marttila S, Nevalainen T, Jylhava J, Mononen N, Kahonen M, et al.
BMC Genomics
. 2016 Feb;
17:103.
PMID: 26861258
Background: Chronological aging-associated changes in the human DNA methylome have been studied by multiple epigenome-wide association studies (EWASs). Certain CpG sites have been identified as aging-associated in multiple studies, and...
8.
Nevalainen T, Kananen L, Marttila S, Jylha M, Hervonen A, Hurme M, et al.
Age (Dordr)
. 2015 Jul;
37(4):9814.
PMID: 26188803
Aging is associated with a pro-inflammatory state, often referred to as inflammaging. The origin of the pro-inflammatory mediators and their role in the pathogenesis of the aging-associated diseases remain poorly...
9.
Lisko I, Tiainen K, Stenholm S, Luukkaala T, Hurme M, Lehtimaki T, et al.
Eur J Clin Nutr
. 2013 Feb;
67(4):420-2.
PMID: 23443829
Data on how body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) are associated with body fat in the oldest-old people are scarce. The purpose of this study...
10.
Haarala A, Kahonen M, Lehtimaki T, Aittoniemi J, Jylhava J, Hutri-Kahonen N, et al.
Clin Exp Immunol
. 2012 Jan;
167(2):309-16.
PMID: 22236008
Human cytomegalovirus (CMV) infection is associated with a higher risk of cardiovascular disease in immunocompromised organ transplant patients. It has been linked with the pathogenesis of elevated arterial blood pressure....