M Holzenberger
Overview
Explore the profile of M Holzenberger including associated specialties, affiliations and a list of published articles.
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18
Citations
371
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Recent Articles
1.
Froment P, Vigier M, Negre D, Fontaine I, Beghelli J, Cosset F, et al.
J Endocrinol
. 2007 Sep;
194(3):557-68.
PMID: 17761895
IGF-I regulates pituitary and gonadal functions, and is pivotal for sexual development and fertility in mammalian species. To better understand the function of autocrine IGF-I in Sertoli cell physiology, we...
2.
Holzenberger M
Horm Res
. 2005 Mar;
62 Suppl 1:89-92.
PMID: 15761239
Inactivation of insulin-like growth factor I (IGF-I) signalling pathways have been shown to extend lifespans in various lower species, including the nematode Caenorhabditis elegans. In order to investigate this relationship...
3.
Kulkarni R, Holzenberger M, Shih D, Ozcan U, Stoffel M, Magnuson M, et al.
Nat Genet
. 2002 Mar;
31(1):111-5.
PMID: 11923875
Regulation of glucose homeostasis by insulin depends on the maintenance of normal beta-cell mass and function. Insulin-like growth factor 1 (Igf1) has been implicated in islet development and differentiated function,...
4.
Leneuve P, Zaoui R, Monget P, Le Bouc Y, Holzenberger M
Biotechniques
. 2001 Dec;
31(5):1156-60, 1162.
PMID: 11730022
Conditional gene targeting, based on Cre-lox or other systems, requires frequent genotyping of transgenic mouse populations and monitoring of tissue-specific Cre recombinatory efficiency. This is currently achieved by Southern analysis...
5.
Ducos B, Cabrol S, Houang M, Perin L, Holzenberger M, Le Bouc Y
J Clin Endocrinol Metab
. 2001 Nov;
86(11):5516-24.
PMID: 11701730
The IGFs, IGF-I and IGF-II, regulate fetal growth by activating IGF type 1 receptors (IGF-IR). We aimed to quantify the binding of IGF-I to its cognate receptors in intrauterine growth-retarded...
6.
Holzenberger M, Hamard G, Zaoui R, Leneuve P, Ducos B, Beccavin C, et al.
Endocrinology
. 2001 Sep;
142(10):4469-78.
PMID: 11564712
Reduced IGF type I receptor levels diminish postnatal growth rate and adult body weight in mice. Here, we studied the impact of experimental IGF receptor deficiency on tissue-specific growth by...
7.
Holzenberger M, Lenzner C, Leneuve P, Zaoui R, Hamard G, Vaulont S, et al.
Nucleic Acids Res
. 2000 Nov;
28(21):E92.
PMID: 11058142
Conditional gene targeting uses the insertion of expression cassettes for the selection of targeted embryonic stem cells. The presence of these cassettes in the final targeted chromosomal locus may affect...
8.
Holzenberger M, Leneuve P, Hamard G, Ducos B, Perin L, BINOUX M, et al.
Endocrinology
. 2000 Jun;
141(7):2557-66.
PMID: 10875258
The insulin-like growth factor (IGF) system is a major regulator of somatic growth in vertebrates. Both ligands (IGF-I and IGF-II) signal via the same IGF receptor (IGF-IR). Classical IGF-IR invalidation...
9.
Holzenberger M, Zaoui R, Leneuve P, Hamard G, Le Bouc Y
Genesis
. 2000 Mar;
26(2):157-9.
PMID: 10686617
No abstract available.
10.
Holzenberger M, Lapointe F, Ayer-Lelievre C
Int J Dev Neurosci
. 2000 Mar;
18(1):69-82.
PMID: 10708908
Insulin-like growth factors (IGFs) are expressed in defined spatiotemporal patterns during the development of the mammalian central nervous system (CNS). Since IGF expression in avian species is less well documented,...