M H M Noteborn
Overview
Explore the profile of M H M Noteborn including associated specialties, affiliations and a list of published articles.
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9
Citations
101
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Recent Articles
1.
Lanz H, Zimmerman R, Brouwer J, Noteborn M, Backendorf C
Cell Death Dis
. 2013 Feb;
4:e487.
PMID: 23392175
Mitotic catastrophe is an oncosuppressive mechanism that senses mitotic failure leading to cell death or senescence. As such, it protects against aneuploidy and genetic instability, and its induction in cancer...
2.
de Smit M, Noteborn M
Curr Top Microbiol Immunol
. 2009 Feb;
331:131-49.
PMID: 19230562
Torque teno viruses (TTVs) share several genomic similarities with the chicken anemia virus (CAV). CAV encodes the protein apoptin that specifically induces apoptosis in (human) tumor cells. Functional studies reveal...
3.
Peng D, Sun J, Wang Y, Tian J, Zhang Y, Noteborn M, et al.
Cancer Gene Ther
. 2006 Jul;
14(1):66-73.
PMID: 16874360
Specificity is a prerequisite for systemic gene therapy of hepatocarcinoma. In vitro, the tumor-specific viral death effector Apoptin selectively induces apoptosis in malignant hepatic cells. Intratumoral treatment of xenografted subcutaneous...
4.
Tolboom T, Zhang Y, Henriquez N, Nelissen R, Toes R, Noteborn M, et al.
Clin Exp Rheumatol
. 2006 Jun;
24(2):142-7.
PMID: 16762148
Objective: Fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA) show characteristics of transformation. Because the chicken anemia virus protein, apoptin, induces apoptosis solely in transformed cells, it was investigated...
5.
Noteborn M
Cell Mol Biol (Noisy-le-grand)
. 2005 Sep;
51(1):49-60.
PMID: 16171564
Apoptin, a protein encoded by an avian virus, induces apoptosis in a tumor-specific way, acts p53-independently and is even stimulated by the anti-apoptotic protein Bcl-2. Activation of upstream caspases is...
6.
Rohn J, Zhang Y, Leliveld S, Danen-van Oorschot A, Henriquez N, Abrahams J, et al.
J Virol
. 2004 Dec;
79(2):1337-8.
PMID: 15613362
No abstract available.
7.
Rohn J, Noteborn M
Apoptosis
. 2004 Jul;
9(3):315-22.
PMID: 15258463
Several natural proteins, including the cellular protein TRAIL and the viral proteins E4orf4 and Apoptin, have been found to exert a tumor-preferential apoptotic activity. These molecules are potential anti-cancer agents...
8.
Danen-van Oorschot A, Voskamp P, Seelen M, Van Miltenburg M, Bolk M, Tait S, et al.
Cell Death Differ
. 2004 Feb;
11(5):564-73.
PMID: 14765135
Apoptin, a protein from chicken anemia virus without an apparent cellular homologue, can induce apoptosis in mammalian cells. Its cytotoxicity is limited to transformed or tumor cells, making Apoptin a...
9.
Leliveld S, Dame R, Rohn J, Noteborn M, Abrahams J
FEBS Lett
. 2004 Jan;
557(1-3):155-8.
PMID: 14741359
Apoptin induces apoptosis specifically in tumour cells, where Apoptin is enriched in the DNA-dense heterochromatin and nucleoli. In vitro, Apoptin interacts with dsDNA, forming large nucleoprotein superstructures likely to be...