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M G Isaguliants

Explore the profile of M G Isaguliants including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 139
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Recent Articles
1.
Zakirova N, Kondrashova A, Golikov M, Ivanova O, Ivanov A, Isaguliants M, et al.
Mol Biol (Mosk) . 2022 Sep; 56(5):795-807. PMID: 36165018
Changes in metabolic pathways are often associated with the development of a wide range of pathologies. Increased glycolysis under conditions of sufficient tissue oxygen supply and its dissociation from the...
2.
Vonsky M, Runov A, Gordeychuk I, Isaguliants M
Biochemistry (Mosc) . 2019 Sep; 84(7):800-816. PMID: 31509730
Human papillomaviruses of high carcinogenic risk (HR HPVs) are major etiological agents of malignant diseases of the cervix, vulva, penis, anal canal, larynx, head, and neck. Prophylactic vaccination against HPV,...
3.
Gordeychuk I, Tukhvatulin A, Petkov S, Abakumov M, Gulyaev S, Tukhvatulina N, et al.
Acta Naturae . 2019 Feb; 10(4):63-69. PMID: 30713763
Common marmosets are small New World primates that have been increasingly used in biomedical research. This report presents efficient protocols for assessment of the parameters of adaptive cell-mediated immunity in...
4.
Latanova A, Petkov S, Kilpelainen A, Jansons J, Latyshev O, Kuzmenko Y, et al.
Sci Rep . 2018 May; 8(1):8078. PMID: 29799015
DNA vaccines require a considerable enhancement of immunogenicity. Here, we optimized a prototype DNA vaccine against drug-resistant HIV-1 based on a weak Th2-immunogen, HIV-1 reverse transcriptase (RT). We designed expression-optimized...
5.
Kichatova V, Kyuregyan K, Soboleva N, Karlsen A, Isaeva O, Isaguliants M, et al.
J Immunol Res . 2018 Mar; 2018:7685371. PMID: 29577052
Amino acid substitutions R70Q/H and L91M in HCV subtype 1b core protein can affect the response to interferon and are associated with the development of hepatocellular carcinoma. We found that...
6.
Baklaushev V, Kilpelainen A, Petkov S, Abakumov M, Grinenko N, Yusubalieva G, et al.
Sci Rep . 2017 Aug; 7(1):7715. PMID: 28798322
Implantation of reporter-labeled tumor cells in an immunocompetent host involves a risk of their immune elimination. We have studied this effect in a mouse model of breast cancer after the...
7.
Smirnova O, Ivanova O, Mukhtarov F, Tunitskaya V, Jansons J, Isaguliants M, et al.
Acta Naturae . 2016 Nov; 8(3):123-127. PMID: 27795852
The hepatitis C virus (HCV) triggers a chronic disease that is often accompanied by a spectrum of liver pathologies and metabolic alterations. The oxidative stress that occurs in the infected...
8.
Shadrina O, Zatsepin T, Agapkina Y, Isaguliants M, Gottikh M
Acta Naturae . 2015 May; 7(1):78-86. PMID: 25927004
Integration of human immunodeficiency virus (HIV-1) DNA into the genome of an infected cell is one of the key steps in the viral replication cycle. The viral enzyme integrase (IN),...
9.
Starodubova E, Isaguliants M, Kuzmenko Y, Latanova A, Krotova O, Karpov V
Acta Naturae . 2014 Apr; 6(1):61-8. PMID: 24772328
Intracellular processing of the antigen encoded by a DNA vaccine is one of the key steps in generating an immune response. Immunization with DNA constructs targeted to the endosomal-lysosomal compartments...
10.
Starodubova E, Isaguliants M, Karpov V
Acta Naturae . 2012 Jun; 2(1):53-60. PMID: 22649628
Immunization with naked genes (DNA-immunization) is a perspective modern approach to prophylactic as well as therapeutic vaccination against pathogens, as well as cancer and allergy. A panel of DNA immunogens...