M G Battelli
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Explore the profile of M G Battelli including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
780
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Recent Articles
1.
Bolognesi A, Polito L, Scicchitano V, Orrico C, Pasquinelli G, Musiani S, et al.
J Biol Regul Homeost Agents
. 2012 Apr;
26(1):97-109.
PMID: 22475101
Saporin-S6 is a single-chain ribosome-inactivating protein (RIP) that has low toxicity in cells and animals. When the protein is bound to a carrier that facilitates cellular uptake, the protein becomes...
2.
Battelli M, Ravaioli M, Musiani S, Scicchitano V, Grazi G, Bolognesi A
J Biol Regul Homeost Agents
. 2011 Mar;
25(1):77-84.
PMID: 21382276
Xanthine oxidoreductase (XOR) leakage into serum has been observed in various types of liver pathology as well as after liver transplantation (LT). We determined the amount of XOR associated with...
3.
Stirpe F, Battelli M
Cell Mol Life Sci
. 2006 Jun;
63(16):1850-66.
PMID: 16799768
Ribosome-inactivating proteins (RIPs), mostly from plants, are enzymes which depurinate rRNA, thus inhibiting protein synthesis. They also depurinate other polynucleotide substrates. The biological activity of RIPs is not completely clarified,...
4.
Bolognesi A, Polito L, Farini V, Bortolotti M, Tazzari P, Ratta M, et al.
J Biol Regul Homeost Agents
. 2006 Apr;
19(3-4):145-52.
PMID: 16602630
An anti-CD38 mAb (IB4) coupled to saporin-S6, a type 1 ribosome-inactivating protein (RIP), was designed for ex vivo or loco-regional therapeutical applications in myeloma and lymphoma. The ability of this...
5.
Battelli M, Polito L, Fala F, Musiani S, Tazzari P, Stirpe F, et al.
J Biol Regul Homeost Agents
. 2006 Apr;
19(3-4):120-9.
PMID: 16602626
Reactive oxygen species (ROS) generated by xanthine oxidoreductase (XOR) were toxic to B lymphoma-derived Raji cells (positive for 8A monoclonal antibody, mAb). The sensitivity of these malignant cells to the...
6.
Battelli M, Musiani S, Buonamici L, Santi S, Riccio M, Maraldi N, et al.
Cell Mol Life Sci
. 2004 Aug;
61(15):1975-84.
PMID: 15289938
Among two-chain ribosome-inactivating proteins (RIPs), volkensin is the most toxic to cells and animals, and is retrogradely axonally transported in the rat central nervous system, being an effective suicide transport...
7.
Battelli M, Musiani S, Tazzari P, Stirpe F
Free Radic Res
. 2002 Jan;
35(6):665-79.
PMID: 11811520
The in vitro toxicity of the reactive oxygen species generating enzyme xanthine oxidoreductase (XOR) to human peripheral blood lymphocytes was studied after stimulation with phytohaemoagglutinin or anti-CD3/CD28 antibodies. Apoptosis and...
8.
Battelli M, Musiani S, Monti B, Buonamici L, Sparapani M, Contestabile A, et al.
Neurochem Int
. 2001 Jun;
39(2):83-93.
PMID: 11408086
Microglial cells, like macrophages, are very sensitive to ricin, a galactose-specific toxic lectin belonging to the family of ribosome-inactivating proteins. This toxin can be taken up by most cells through...
9.
Battelli M, Musiani S, Valgimigli M, Gramantieri L, Tomassoni F, Bolondi L, et al.
Am J Gastroenterol
. 2001 Apr;
96(4):1194-9.
PMID: 11316169
Objectives: High concentrations of serum xanthine oxidase (XO) have been reported during human liver disease and hepatocyte injury in experimental settings. However, it is unclear whether this elevation reflects hepatocyte...
10.
Battelli M, Abbondanza A, Musiani S, Buonamici L, Strocchi P, Tazzari P, et al.
Clin Chim Acta
. 1999 Apr;
281(1-2):147-58.
PMID: 10217635
Xanthine oxidase was purified from human milk and used to immunise rabbits. A competitive immunoenzymatic assay with purified enzyme and rabbit antiserum was optimised to measure xanthine oxidase in human...