M F Tuite
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Explore the profile of M F Tuite including associated specialties, affiliations and a list of published articles.
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119
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3579
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Recent Articles
1.
Tuite M, McLaughlin C
Curr Genet
. 2013 Nov;
7(6):421-6.
PMID: 24173447
The effects of polyamines (spermidine and putrescine) on yeast suppressor tRNA-mediated readthrough of amber and UGA termination codons, in a homologous cell-free system, was examined. The efficiency of readthrough in...
2.
Freedman R, Greenall C, Jenkins N, Tuite M
Cytotechnology
. 2012 Feb;
18(1-2):77-82.
PMID: 22358639
The exit of newly-synthesized proteins from the lumen of the endoplasmic reticulum (ER) is the rate-determining step in protein secretion. Only correctly-folded and fully-assembled proteins exit the ER and progress...
3.
Cole D, Ridout M, Morgan B, Byrne L, Tuite M
Biometrics
. 2007 Apr;
63(4):1023-30.
PMID: 17425634
A deterministic formula is commonly used to approximate the expected generation number of a population of growing cells. However, this can give misleading results because it does not allow for...
4.
Ridout M, Cole D, Morgan B, Byrne L, Tuite M
Biometrics
. 2006 Dec;
62(4):1216-23.
PMID: 17156297
Approximations to the Malthusian parameter of an age-dependent branching process are obtained in terms of the moments of the lifetime distribution, by exploiting a link with renewal theory. In several...
5.
Cole D, Morgan B, Ridout M, Byrne L, Tuite M
Math Med Biol
. 2004 Nov;
21(4):369-95.
PMID: 15567890
Certain yeast cells contain proteins that behave like the mammalian prion PrP and are called yeast prions. The yeast prion protein Sup35p can exist in one of two stable forms,...
6.
OSullivan J, Mihr M, Santos M, Tuite M
Gene
. 2001 Sep;
275(1):133-40.
PMID: 11574161
In a number of Candida species the 'universal' leucine codon CUG is decoded as serine. To help understand the evolution of such a codon reassignment we have analyzed the Candida...
7.
Ferreira P, Ness F, Edwards S, Cox B, Tuite M
Mol Microbiol
. 2001 Jul;
40(6):1357-69.
PMID: 11442834
In the yeast Saccharomyces cerevisiae, Sup35p (eRF3), a subunit of the translation termination complex, can take up a prion-like, self-propagating conformation giving rise to the non-Mendelian [PSI+] determinant. The replication...
8.
Parham S, Resende C, Tuite M
EMBO J
. 2001 May;
20(9):2111-9.
PMID: 11331577
The nuclear-encoded Sup35p protein is responsible for the prion-like [PSI(+)] determinant of yeast, with Sup35p existing largely as a high molecular weight aggregate in [PSI(+)] strains. Here we show that...
9.
OSullivan J, Mihr M, Santos M, Tuite M
Yeast
. 2001 Feb;
18(4):313-22.
PMID: 11223940
A number of Candida species translate the standard leucine-CUG codon as serine using a novel ser-tRNA(CAG). This tRNA, which has an unusual anticodon stem-loop structure, has been implicated in the...
10.
OSullivan J, Davenport J, Tuite M
Trends Genet
. 2001 Feb;
17(1):20-2.
PMID: 11163917
The in silico translation of open reading frames, using the 'universal genetic code', must be approached with caution. The uncovering of a number of codon reassignments in nuclear and organellar...