M Eilers
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Explore the profile of M Eilers including associated specialties, affiliations and a list of published articles.
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67
Citations
3482
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Recent Articles
1.
Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson M, Schmitz W, Wach S, et al.
Nat Commun
. 2021 Aug;
12(1):5066.
PMID: 34417456
Prostate cancer (PCa) shows strong dependence on the androgen receptor (AR) pathway. Here, we show that squalene epoxidase (SQLE), an enzyme of the cholesterol biosynthesis pathway, is overexpressed in advanced...
2.
Denk S, Schmidt S, Schurr Y, Schwarz G, Schote F, Diefenbacher M, et al.
Int J Colorectal Dis
. 2021 Jun;
36(9):2061.
PMID: 34086088
No abstract available.
3.
Denk S, Schmidt S, Schurr Y, Schwarz G, Schote F, Diefenbacher M, et al.
Int J Colorectal Dis
. 2020 Oct;
36(5):911-918.
PMID: 33078202
Background: Deregulated expression of MYC is a driver of colorectal carcinogenesis, suggesting that decreasing MYC expression may have significant therapeutic value. CIP2A is an oncogenic factor that regulates MYC expression....
4.
Jung L, Gebhardt A, Koelmel W, Ade C, Walz S, Kuper J, et al.
Oncogene
. 2016 Oct;
36(14):1911-1924.
PMID: 27748763
MYC genes have both essential roles during normal development and exert oncogenic functions during tumorigenesis. Expression of a dominant-negative allele of MYC, termed OmoMYC, can induce rapid tumor regression in...
5.
Leich E, Weissbach S, Klein H, Grieb T, Pischimarov J, Stuhmer T, et al.
Blood Cancer J
. 2013 Feb;
3:e102.
PMID: 23396385
Multiple myeloma (MM) is a largely incurable plasma cell malignancy with a poorly understood and heterogeneous clinical course. To identify potential, functionally relevant somatic mutations in MM, we performed whole-exome...
6.
Leikam C, Hufnagel A, Walz S, Kneitz S, Fekete A, Muller M, et al.
Oncogene
. 2013 Jan;
33(6):771-82.
PMID: 23353821
The development of malignant melanoma is a highly complex process, which is still poorly understood. A majority of human melanomas are found to express a few oncogenic proteins, such as...
7.
Muller J, Eilers M
Ernst Schering Found Symp Proc
. 2009 Feb;
(1):99-113.
PMID: 19198066
The level of Myc proteins is a critical determinant of cellular proliferation and apoptosis. Ubiquitination of Myc plays a key role in controlling protein levels by stimulating proteasomal degradation of...
8.
Spahn T, Kampmann W, Eilers M, Mueller M, Rodeck B
Endoscopy
. 2007 Jul;
39 Suppl 1:E217.
PMID: 17614046
No abstract available.
9.
Kleine-Kohlbrecher D, Adhikary S, Eilers M
Curr Top Microbiol Immunol
. 2006 Apr;
302:51-62.
PMID: 16620025
Myc proteins are nuclear proteins that exert their biological functions at least in part through the transcriptional regulation of large sets of target genes. Recent microarray analyses show that several...
10.
Ritter M, Kattmann D, Teichler S, Hartmann O, Samuelsson M, Burchert A, et al.
Leukemia
. 2006 Jan;
20(3):437-43.
PMID: 16424870
Acute myeloid leukemia (AML) is a heterogeneous disease with multiple different cytogenetic and molecular aberrations contributing to leukemic transformation. We compared gene expression profiles of 4608 genes using cDNA-arrays from...