M E Larkum
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Explore the profile of M E Larkum including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Phillips W, Larkum M, Harley C, Silverstein S
Neurosci Conscious
. 2018 Jun;
2016(1):niw015.
PMID: 29877512
Neocortical pyramidal cells can integrate two classes of input separately and use one to modulate response to the other. Their tuft dendrites are electrotonically separated from basal dendrites and soma...
2.
Larkum M, Phillips W
Behav Brain Sci
. 2017 Mar;
39:e215.
PMID: 28347375
We summarize evidence that input to the apical tufts of neocortical pyramidal cells modulates their response to basal input. Because this apical amplification and disamplification provide intracortical mechanisms for prioritization,...
3.
Larkum M, Zhu J, Sakmann B
J Physiol
. 2001 Jun;
533(Pt 2):447-66.
PMID: 11389204
1. Double, triple and quadruple whole-cell voltage recordings were made simultaneously from different parts of the apical dendritic arbor and the soma of adult layer 5 (L5) pyramidal neurons. We...
4.
Berger T, Larkum M, Luscher H
J Neurophysiol
. 2001 Feb;
85(2):855-68.
PMID: 11160518
Despite the wealth of recent research on active signal propagation along the dendrites of layer V neocortical pyramidal neurons, there is still little known regarding the traffic of subthreshold synaptic...
5.
Larkum M, Kaiser K, Sakmann B
Proc Natl Acad Sci U S A
. 1999 Dec;
96(25):14600-4.
PMID: 10588751
Action potentials in juvenile and adult rat layer-5 neocortical pyramidal neurons can be initiated at both axonal and distal sites of the apical dendrite. However, little is known about the...
6.
Larkum M, Zhu J, Sakmann B
Nature
. 1999 Apr;
398(6725):338-41.
PMID: 10192334
Pyramidal neurons in layer 5 of the neocortex of the brain extend their axons and dendrites into all layers. They are also unusual in having both an axonal and a...
7.
Larkum M, Launey T, Dityatev A, Luscher H
J Neurophysiol
. 1998 Aug;
80(2):924-35.
PMID: 9705479
We examined the attenuation and integration of spontaneous excitatory postsynaptic potentials (sEPSPs) in the dendrites of presumed motoneurons (MNs) of organotypic rat spinal cord cultures. Simultaneous whole cell recordings in...
8.
Luscher H, Larkum M
J Neurophysiol
. 1998 Aug;
80(2):715-29.
PMID: 9705463
Regardless of the site of current injection, action potentials usually originate at or near the soma and propagate decrementally back into the dendrites. This phenomenon has been observed in neocortical...
9.
Larkum M, Rioult M, Luscher H
J Neurophysiol
. 1996 Jan;
75(1):154-70.
PMID: 8822549
1. We examined the propagation of action potentials in the dendrites of ventrally located presumed motoneurons of organotypic rat spinal cord cultures. Simultaneous patch electrode recordings were made from the...
10.
Larkum M, Warren D, Bennett M
J Auton Nerv Syst
. 1994 Mar;
46(3):175-88.
PMID: 8014371
A study has been made of the changes in calcium concentration in the calyciform nerve terminal ([Ca]c) and in the neurone soma ([Ca]s) of avian ciliary ganglion cells following tetanic...