M E Caplin
Overview
Explore the profile of M E Caplin including associated specialties, affiliations and a list of published articles.
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36
Citations
1091
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0
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Recent Articles
21.
Samonakis D, Quaglia A, Joshi N, Tibballs J, Nagree A, Triantos C, et al.
Eur J Gastroenterol Hepatol
. 2005 Oct;
17(11):1229-32.
PMID: 16215436
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder, with variable clinical manifestations and unpredictable course, associated with an increased incidence of various tumours. Plexiform neurofibromas are hallmark lesions...
22.
Stubbs M, Khan K, Wickremasinghe R, Ganeshaguru K, Caplin M
Oncol Rep
. 2005 Sep;
14(4):1055-8.
PMID: 16142371
The gastrin CCK2 pathway has been implicated in the development of various cancers including leukaemia. An autocrine or intracrine pathway may exist in the leukaemia cell that is involved in...
23.
Cwikla J, Buscombe J, Mielcarek W, Caplin M, Watkinson A, Hilson A
Nucl Med Rev Cent East Eur
. 2003 Nov;
4(1):27-33.
PMID: 14600962
Background: The diagnostic approach that should be used in disseminated neuroendocrine tumours (NET) remains a significant clinical problem. A novel approach has been the use of 111In Octreotide as functional...
24.
Goede A, Caplin M, Winslet M
Br J Surg
. 2003 Nov;
90(11):1317-22.
PMID: 14598408
Background: Appendiceal carcinoid tumours are found in 0.3-0.9 per cent of patients undergoing appendicectomy. Controversy exists over the management following appendicectomy, especially with regard to the role of right hemicolectomy...
25.
Garland J, Buscombe J, Bouvier C, Bouloux P, Chapman M, Chow A, et al.
Aliment Pharmacol Ther
. 2003 Feb;
17(3):437-44.
PMID: 12562458
Background: Somatostatin analogues are the best therapy for controlling the symptoms of malignant carcinoid syndrome. Octreotide acetate given as subcutaneous injection up to three times daily, intramuscular Lanreotide injection given...
26.
McStay M, Caplin M
Minerva Med
. 2002 Nov;
93(5):389-401.
PMID: 12410171
Carcinoid tumours are relatively rare neoplasms that often present as diagnostic dilemmas due to obscure or non-specific symptomatology. The ability of carcinoid tumours to cause clinical symptoms by secretion of...
27.
Brett B, Smith S, Bouvier C, Michaeli D, Hochhauser D, Davidson B, et al.
J Clin Oncol
. 2002 Oct;
20(20):4225-31.
PMID: 12377966
Purpose: The prognosis for advanced pancreatic cancer remains poor. Gastrin acts as a growth factor for pancreatic cancer. We describe the first study of the antigastrin immunogen G17DT in pancreatic...
28.
Watson S, Clarke P, Morris T, Caplin M
Cancer Res
. 2000 Nov;
60(20):5902-7.
PMID: 11059789
Serum gastrin is known to be elevated in patients with liver-metastasizing colon cancer; thus, cholecystokinin (CCK) B/gastrin receptors may also be up-regulated. A liver-invasive model of colon cancer was established...
29.
30.
Caplin M, Mielcarek W, Buscombe J, Jones A, Croasdale P, Cooper M, et al.
Nucl Med Commun
. 2000 Mar;
21(1):97-102.
PMID: 10717909
Disseminated neuroendocrine tumours are difficult to treat and are generally not responsive to radiotherapy or chemotherapy. Nuclear medicine techniques using a radiolabelled somatostatin analogue, 111In-Octreotide, have been used for the...