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M D Orellana

Explore the profile of M D Orellana including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 123
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Recent Articles
1.
de Cassia Viu Carrara R, Fontes A, Abraham K, Orellana M, Haddad S, Palma P, et al.
Clin Transl Oncol . 2017 Sep; 20(4):542-549. PMID: 28905209
Purpose: The fusion gene BCR-ABL has an important role to the progression of chronic myeloid leukemia (CML) and several signaling pathways have been characterized as responsible for the terminal blastic...
2.
Dotoli G, De Santis G, Orellana M, de Lima Prata K, Caruso S, Fernandes T, et al.
Bone Marrow Transplant . 2017 Mar; 52(6):859-862. PMID: 28287644
Acute GvHD (aGvHD) is a life-threatening complication of hematopoietic stem cell transplantation. Frontline therapy for aGvHD consists of corticosteroid administration. However, ∼25% of the patients have a steroid-refractory disease, a...
3.
De Santis G, Garcia-Silva A, Chiaramonte N, Orellana M, Prado Jr B, Oliveira L, et al.
Transfus Med . 2016 May; 26(4):297-300. PMID: 27237104
Objectives: Evaluate whether poor mobilisers had delayed haematopoietic (neutrophil and platelet) recovery despite receiving similar cell dose as good mobilisers. Background: Autologous haematopoietic progenitor cell (HPC) transplantation is indicated to...
4.
Pinto M, Nicolete L, Rodrigues E, Palma P, Orellana M, Kashima S, et al.
Braz J Med Biol Res . 2013 Sep; 46(8):676-80. PMID: 24036939
Multipotent mesenchymal stromal cells (MSCs) were first isolated from bone marrow and then from various adult tissues including placenta, cord blood, deciduous teeth, and amniotic fluid. MSCs are defined or...
5.
De Santis G, de Pina Almeida Prado Jr B, de Lima Prata K, Brunetta D, Orellana M, Palma P, et al.
Bone Marrow Transplant . 2011 Sep; 47(7):993-4. PMID: 21927040
No abstract available.
6.
Carrara R, Orellana M, Fontes A, Palma P, Kashima S, Mendes M, et al.
Braz J Med Biol Res . 2007 Jan; 40(1):57-67. PMID: 17224997
Bone marrow is a heterogeneous cell population which includes hematopoietic and mesenchymal progenitor cells. Dysregulated hematopoiesis occurs in chronic myelogenous leukemia (CML), being caused at least in part by abnormalities...
7.
Goes E, Borges J, Covas D, Orellana M, Palma P, Morais F, et al.
Transfusion . 2006 Jan; 46(1):34-40. PMID: 16398728
Background: To identify the most appropriate dose for the prevention of transfusion-associated graft-versus-host disease, the radiosensitivity of T cells has been determined in blood bags irradiated with X-rays produced by...
8.
Covas D, Siufi J, Silva A, Orellana M
Braz J Med Biol Res . 2003 Aug; 36(9):1179-83. PMID: 12937783
Bone marrow contains a population of stem cells that can support hematopoiesis and can differentiate into different cell lines including adipocytes, osteocytes, chondrocytes, myocytes, astrocytes, and tenocytes. These cells have...