M D Norenberg
Overview
Explore the profile of M D Norenberg including associated specialties, affiliations and a list of published articles.
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157
Citations
3835
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Recent Articles
1.
Jayakumar A, Taherian M, Panickar K, Shamaladevi N, Rodriguez M, Price B, et al.
Neurochem Res
. 2017 Nov;
43(2):397-406.
PMID: 29150743
Brain edema and the associated increase in intracranial pressure are major consequences of traumatic brain injury (TBI) that accounts for most early deaths after TBI. We recently showed that acute...
2.
Jayakumar A, Apeksha A, Norenberg M
Neurochem Res
. 2016 Nov;
42(3):858-875.
PMID: 27878658
Matricellular proteins (MCPs) are actively expressed non-structural proteins present in the extracellular matrix, which rapidly turnover and possess regulatory roles, as well as mediate cell-cell interactions. MCPs characteristically contain binding...
3.
Jayakumar A, Bak L, Rama Rao K, Waagepetersen H, Schousboe A, Norenberg M
Neurochem Res
. 2016 Jan;
41(1-2):307-15.
PMID: 26729365
Traumatic brain injury (TBI) is a devastating neurological disorder that usually presents in acute and chronic forms. Brain edema and associated increased intracranial pressure in the early phase following TBI...
4.
Sulfonylurea receptor 1 contributes to the astrocyte swelling and brain edema in acute liver failure
Jayakumar A, Valdes V, Tong X, Shamaladevi N, Gonzalez W, Norenberg M
Transl Stroke Res
. 2014 Jan;
5(1):28-37.
PMID: 24443056
Astrocyte swelling (cytotoxic brain edema) is the major neurological complication of acute liver failure (ALF), a condition in which ammonia has been strongly implicated in its etiology. Ion channels and...
5.
Jayakumar A, Ruiz-Cordero R, Tong X, Norenberg M
Arch Biochem Biophys
. 2013 Apr;
536(2):171-5.
PMID: 23567839
Brain edema is a major neurological complication of acute liver failure (ALF) and swelling of astrocytes (cytotoxic brain edema) is the most prominent neuropathological abnormality in this condition. Elevated brain...
6.
Jayakumar A, Norenberg M
Metab Brain Dis
. 2012 Oct;
28(2):183-6.
PMID: 23099995
Brain edema and the subsequent increase in intracranial pressure are major neurological complications of acute liver failure (ALF), and swelling of astrocytes (cytotoxic brain edema) is the most prominent neuropathological...
7.
Jayakumar A, Tong X, Ospel J, Norenberg M
Neuroscience
. 2012 May;
218:305-16.
PMID: 22609932
Brain edema is an important complication of acute hepatic encephalopathy (AHE), and astrocyte swelling is largely responsible for its development. Elevated blood and brain ammonia levels have been considered as...
8.
Jayakumar A, Bethea J, Tong X, Gomez J, Norenberg M
Neurobiol Dis
. 2010 Nov;
41(2):498-507.
PMID: 21087666
Astrocyte swelling and brain edema are major complications of the acute form of hepatic encephalopathy (acute liver failure, ALF). While elevated brain ammonia level is a well-known etiological factor in...
9.
Rao K, Jayakumar A, Reddy P, Tong X, Curtis K, Norenberg M
Glia
. 2010 Jul;
58(12):1490-9.
PMID: 20648640
Manganese in excess is neurotoxic and causes CNS injury resembling that of Parkinson's disease. In brain, astrocytes predominantly take up and accumulate manganese and are thus vulnerable to its toxicity....
10.
Moriyama M, Jayakumar A, Tong X, Norenberg M
J Neurosci Res
. 2010 Jul;
88(11):2450-8.
PMID: 20623534
Cytotoxic brain edema, usually a consequence of astrocyte swelling, is an important complication of stroke, traumatic brain injury, hepatic encephalopathy, and other neurological disorders. Although mechanisms underlying astrocyte swelling are...