M D Brendel
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Explore the profile of M D Brendel including associated specialties, affiliations and a list of published articles.
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53
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555
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Recent Articles
1.
Schloot N, Roden M, Bornstein S, Brendel M
Dtsch Med Wochenschr
. 2011 Jan;
136(5):172-5.
PMID: 21271474
INTERVENTIONAL APPROACHES TO BETA CELL PRESERVATION: In a pilot study, initial attempts at primary prevention by preserving islet beta cells have been successful with highly hydrolyzed milk formula in children...
2.
Ludwig B, Zimerman B, Steffen A, Yavriants K, Azarov D, Reichel A, et al.
Horm Metab Res
. 2010 Oct;
42(13):918-22.
PMID: 21031332
Islet transplantation as a biological β-cell replacement therapy has emerged as a promising option for achieving restoration of metabolic control in type 1 diabetes patients. However, partial or complete loss...
3.
Eckhard M, Schindler R, Renner F, Schief W, Padberg W, Weimer R, et al.
Transplant Proc
. 2009 Sep;
41(6):2544-5.
PMID: 19715971
Background: New-onset diabetes mellitus after organ transplantation (PTDM) significantly impairs patient and organ survival. Published rates of PTDM range from 2% to 54%, depending on the definition. Objectives: To analyze...
4.
Jaeger C, Winter S, Eckhard M, Hardt P, Brendel M, Bretzel R
Acta Diabetol
. 2008 May;
45(3):191-4.
PMID: 18493700
To evaluate ex vivo/in vitro the binding and dissociation characteristics and the level of crossreactivity of insulin antibodies and insulin autoantibodies directed to three different insulin molecules (human, bovine and...
5.
Niu X, Perakakis N, Laubner K, Limbert C, Stahl T, Brendel M, et al.
Diabetologia
. 2007 May;
50(7):1433-41.
PMID: 17479246
Aims/hypothesis: The Krüppel-like factor 11 (KLF11; TIEG2), a pancreas-enriched Sp1-like transcription factor, is a known negative regulator of pancreatic exocrine cell growth. A recent study indicated KLF11-induced activation of the...
6.
Schrader J, Rennekamp W, Niebergall U, Schoppet M, Jahr H, Brendel M, et al.
Diabetologia
. 2007 Apr;
50(6):1243-7.
PMID: 17443309
Aims/hypothesis: Pro-inflammatory cytokines play a crucial role in immune-mediated beta cell destruction, an essential mechanism in the pathogenesis of type 1 diabetes mellitus. Microarray analysis recently identified osteoprotegerin (OPG; now...
7.
Bretzel R, Eckhard M, Jahr H, Brendel M
Dtsch Med Wochenschr
. 2006 Apr;
131(16):903-6.
PMID: 16625486
No abstract available.
8.
Dieterle C, Brendel M, Seissler J, Eckhard M, Bretzel R, Landgraf R
Internist (Berl)
. 2006 Apr;
47(5):489-96, 498-501.
PMID: 16575611
The long-term normalization of glucose metabolism - a prerequisite for the prevention of secondary complications in patients with diabetes mellitus - is only possible by transplantation of a whole pancreas...
9.
Staiger K, Stefan N, Staiger H, Brendel M, Brandhorst D, Bretzel R, et al.
J Clin Endocrinol Metab
. 2005 Oct;
90(12):6707-13.
PMID: 16204361
Context: The adipokine adiponectin has insulin-sensitizing, antiatherogenic, and antiinflammatory properties. Mouse and human adiponectin receptor-1 and -2 have been cloned, both of which are expressed in various tissues and mediate...
10.
Trumper J, Ross D, Jahr H, Brendel M, Goke R, Horsch D
Diabetologia
. 2005 Jul;
48(8):1534-40.
PMID: 15995848
Aims/hypothesis: Glucose and glucagon-like peptide-1 have been shown to activate extracellular signal-regulated kinase (ERK) and phosphoinositide 3-kinase in beta cells. We examined the contributions of the small GTPases Rap and...