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M Cristina Keightley

Explore the profile of M Cristina Keightley including associated specialties, affiliations and a list of published articles. Areas
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Citations 86
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Recent Articles
1.
Atkin-Smith G, Santavanond J, Light A, Rimes J, Samson A, Er J, et al.
Nat Commun . 2024 Oct; 15(1):8802. PMID: 39438460
Endothelial cells are integral components of all vasculature within complex organisms. As they line the blood vessel wall, endothelial cells are constantly exposed to a variety of molecular factors and...
2.
Cao H, Naik S, Amann-Zalcenstein D, Hickey P, Salim A, Cao B, et al.
Blood Adv . 2023 Aug; 7(21):6506-6519. PMID: 37567157
Hematopoiesis produces diverse blood cell lineages to meet the basal needs and sudden demands of injury or infection. A rapid response to such challenges requires the expansion of specific lineages...
3.
Manley H, Potter D, Heddleston J, Chew T, Keightley M, Lieschke G
J Leukoc Biol . 2020 Apr; 108(2):455-468. PMID: 32323898
Neutrophil and macrophage (Mϕ) migration underpin the inflammatory response. However, the fast velocity, multidirectional instantaneous movement, and plastic, ever-changing shape of phagocytes confound high-resolution intravital imaging. Lattice lightsheet microscopy (LLSM)...
4.
Mathiyalagan N, Miles L, Anderson P, Wilanowski T, Grills B, McDonald S, et al.
Genes (Basel) . 2019 Nov; 10(11). PMID: 31683705
The () and vertebrate - () transcription factors are among the most critical genes for epithelial development, maintenance and homeostasis, and are remarkably well conserved from fungi to humans. Mutations...
5.
Pazhakh V, Clark S, Keightley M, Lieschke G
Sci Rep . 2017 Mar; 7:44455. PMID: 28281657
Granulocyte colony-stimulating factor (GCSF) and its receptor (GCSFR), also known as CSF3 and CSF3R, are required to maintain normal neutrophil numbers during basal and emergency granulopoiesis in humans, mice and...
6.
Keightley M, Wong B, Lieschke G
Curr Biol . 2013 Jan; 23(2):R76-8. PMID: 23347945
The transfer of immunity from mother to offspring is widespread in animals. The father's contribution to this is usually negligible. However, in a sex-role reversed pipefish where fathers do the...
7.
Pase L, Layton J, Wittmann C, Ellett F, Nowell C, Reyes-Aldasoro C, et al.
Curr Biol . 2012 Sep; 22(19):1818-24. PMID: 22940471
Prompt neutrophil arrival is critical for host defense immediately after injury [1-3]. Following wounding, a hydrogen peroxide (H(2)O(2)) burst generated in injured tissues is the earliest known leukocyte chemoattractant [4]....