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M Capovilla

Explore the profile of M Capovilla including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Valmary-Degano S, Colpart P, Villeneuve L, Monnien F, MHamdi L, Lang Averous G, et al.
Eur J Surg Oncol . 2017 Jun; 43(10):1915-1923. PMID: 28619621
Background: Epithelioid peritoneal malignant mesothelioma (EPMM) is the most common subtype of this aggressive tumor. We compared two antibodies against PD-L1, a recent theranostic biomarker, and evaluated the prognostic value...
2.
Capovilla M, Kambris Z, Botas J
Development . 2001 Mar; 128(8):1221-30. PMID: 11262224
Hox genes control segment identity in the mesoderm as well as in other tissues. Most evidence indicates that Hox genes act cell-autonomously in muscle development, although this remains a controversial...
3.
Tzou P, Ohresser S, Ferrandon D, Capovilla M, Reichhart J, Lemaitre B, et al.
Immunity . 2000 Dec; 13(5):737-48. PMID: 11114385
The production of antimicrobial peptides is an important aspect of host defense in multicellular organisms. In Drosophila, seven antimicrobial peptides with different spectra of activities are synthesized by the fat...
4.
Fernandez-Funez P, de Gouyon B, She W, Luchak J, Martinez P, Turiegano E, et al.
Nature . 2000 Nov; 408(6808):101-6. PMID: 11081516
A growing number of human neurodegenerative diseases result from the expansion of a glutamine repeat in the protein that causes the disease. Spinocerebellar ataxia type 1 (SCA1) is one such...
5.
Lagueux M, Perrodou E, Levashina E, Capovilla M, Hoffmann J
Proc Natl Acad Sci U S A . 2000 Oct; 97(21):11427-32. PMID: 11027343
We show that Drosophila expresses four genes encoding proteins with significant similarities with the thiolester-containing proteins of the complement C3/alpha(2)-macroglobulin superfamily. The genes are transcribed at a low level during...
6.
Capovilla M, Botas J
Development . 1998 Nov; 125(24):4949-57. PMID: 9811579
Here we investigate the mechanisms by which Hox genes compete for the control of positional identity. Functional dominance is often observed where different Hox genes are co-expressed, and frequently the...
7.
Chan S, Jaffe L, Capovilla M, Botas J, Mann R
Cell . 1994 Aug; 78(4):603-15. PMID: 7915199
The Ultrabithorax (Ubx) and Antennapedia (Antp) genes of Drosophila encode homeodomain proteins that have very similar DNA binding specificities in vitro but specify the development of different segmental patterns in...
8.
Capovilla M, Brandt M, Botas J
Cell . 1994 Feb; 76(3):461-75. PMID: 7906203
Drosophila homeotic genes encode transcription factors thought to control segmental identity by regulating expression of largely unknown target genes. The formation of the second midgut constriction requires the Ultrabithorax (Ubx)...
9.
Qian S, Capovilla M, Pirrotta V
EMBO J . 1993 Oct; 12(10):3865-77. PMID: 8404855
The core activity of the Ubx gene enhancer BRE (bx region enhancer) is encoded within a 500 bp module. bx DNA outside this active module increases the level of expression,...
10.
Capovilla M, Eldon E, Pirrotta V
Development . 1992 Jan; 114(1):99-112. PMID: 1576969
The sequence of a cDNA from the giant gene of Drosophila shows that its product has a basic domain followed by a leucine zipper motif. Both features contain characteristic conserved...