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M C Verhaar

Explore the profile of M C Verhaar including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 992
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Recent Articles
1.
Dilmen E, Olde Hanhof C, Yousef Yengej F, Ammerlaan C, Rookmaaker M, Orhon I, et al.
Exp Cell Res . 2024 Nov; 444(1):114342. PMID: 39566879
Tubuloids are advanced in vitro models obtained from adult human or mouse kidney cells with great potential for modelling kidney function in health and disease. Here, we developed a polarized...
2.
Pieters T, van Dam M, Sikma M, van Arkel A, Veldhuis W, Verhaar M, et al.
Sci Rep . 2024 Sep; 14(1):21098. PMID: 39256537
Estimating glomerular filtration (eGFR) after Continuous Renal Replacement Therapy (CRRT) is important to guide drug dosing and to assess the need to re-initiate CRRT. Standard eGFR equations cannot be applied...
3.
van Drie R, van de Wouw J, Zandbergen L, Dehairs J, Swinnen J, Mulder M, et al.
Basic Res Cardiol . 2024 May; 119(5):869-887. PMID: 38796544
Multiple common cardiovascular comorbidities produce coronary microvascular dysfunction. We previously observed in swine that a combination of diabetes mellitus (DM), high fat diet (HFD) and chronic kidney disease (CKD) induced...
4.
Olde Hanhof C, Dilmen E, Yousef Yengej F, Latta F, Ammerlaan C, Schreurs J, et al.
Front Cell Dev Biol . 2023 Feb; 11:1086823. PMID: 36760360
Kidney tubuloids are cell models that are derived from human or mouse renal epithelial cells and show high similarities with their counterparts. Tubuloids grow polarized in 3D, allow for long-term...
5.
Pieters T, Veldhuis W, Moeskops P, de Vos B, Verhaar M, Haitjema S, et al.
Sci Rep . 2022 May; 12(1):9013. PMID: 35637278
Assessment of daily creatinine production and excretion plays a crucial role in the estimation of renal function. Creatinine excretion is estimated by creatinine excretion equations and implicitly in eGFR equations...
6.
Niemantsverdriet M, Pieters T, Hoefer I, Verhaar M, Joles J, van Solinge W, et al.
PLoS One . 2021 Dec; 16(12):e0261977. PMID: 34965267
Background: Acquiring a reliable estimate of glomerular filtration rate (eGFR) at the emergency department (ED) is important for clinical management and for dosing renally excreted drugs. However, renal function formulas...
7.
Hageman S, Dorresteijn J, Bots M, Asselbergs F, Westerink J, van der Meulen M, et al.
Eur J Prev Cardiol . 2021 May; 29(4):635-644. PMID: 34009323
Aims: To determine the (cost)-effectiveness of blood pressure lowering, lipid-lowering, and antithrombotic therapy guided by predicted lifetime benefit compared to risk factor levels in patients with symptomatic atherosclerotic disease. Methods...
8.
Pei J, Schuldt M, Nagyova E, Gu Z, El Bouhaddani S, Yiangou L, et al.
Clin Epigenetics . 2021 Mar; 13(1):61. PMID: 33757590
Background: Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the cardiac muscle, frequently caused by mutations in MYBPC3. However, little is known about the upstream pathways and key...
9.
Jansz T, Goto N, van Ballegooijen A, Willems H, Verhaar M, van Jaarsveld B
Osteoporos Int . 2019 Nov; 31(3):515-524. PMID: 31728605
Introduction: Vertebral fractures are often overlooked, but even undiagnosed vertebral fractures negatively impact physical functioning, quality of life, and mortality. The risk of vertebral fractures in end-stage renal disease (ESRD)...
10.
Goto N, Weststrate A, Oosterlaan F, Verhaar M, Willems H, Emmelot-Vonk M, et al.
Osteoporos Int . 2019 Nov; 31(1):13-29. PMID: 31720721
Patients with chronic kidney disease (CKD) are more likely to experience falls and fractures due to renal osteodystrophy and the high prevalence of risk factors for falls. However, it is...