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M C Nawijn

Explore the profile of M C Nawijn including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 859
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Recent Articles
11.
Ketelaar M, Nawijn M, Shaw D, Koppelman G, Sayers I
Clin Exp Allergy . 2016 Feb; 46(6):884-7. PMID: 26850082
Background: Interleukin-33 (IL-33) has been subject of extensive study in the context of inflammatory disorders, particularly in asthma. Many human biological samples, including serum, have been used to determine the...
12.
de Vries M, Hesse L, Jonker M, van den Berge M, van Oosterhout A, Heijink I, et al.
Am J Physiol Lung Cell Mol Physiol . 2015 Oct; 309(11):L1344-53. PMID: 26453516
Most patients with allergic asthma are sensitized to house dust mite (HDM). The allergenicity of HDM largely depends on disruption of the integrity and proinflammatory activation of the airway epithelium....
13.
de Vries M, Heijink I, Gras R, den Boef L, Reinders-Luinge M, Pouwels S, et al.
Am J Physiol Lung Cell Mol Physiol . 2014 May; 307(3):L240-51. PMID: 24816488
Exposure to cigarette smoke (CS) is the main risk factor for developing chronic obstructive pulmonary disease and can induce airway epithelial cell damage, innate immune responses, and airway inflammation. We...
14.
Heijink I, Nawijn M, Hackett T
Clin Exp Allergy . 2014 Mar; 44(5):620-30. PMID: 24612268
The integrity of the airway epithelium in patients with asthma is often disrupted, with loss of epithelial cell-cell contacts. Airway epithelial barrier dysfunction may have important implications for asthma, because...
15.
Bidad K, Nawijn M, van Oosterhout A, van der Heide S, Oude Elberink J
Cytometry B Clin Cytom . 2013 Dec; PMID: 24327387
Background: There is need for an accurate diagnostic test in mastocytosis patients with wasp venom allergy (WVA) and monitoring of these patients during immunotherapy (IT). In this study, we aimed...
16.
Pouwels S, Heijink I, Ten Hacken N, Vandenabeele P, Krysko D, Nawijn M, et al.
Mucosal Immunol . 2013 Oct; 7(2):215-26. PMID: 24150257
Chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by sustained neutrophilic airway inflammation, is caused by chronic exposure to noxious stimuli, e.g., cigarette smoke. This chronic exposure can...
17.
Post S, Nawijn M, Jonker M, Kliphuis N, van den Berge M, van Oosterhout A, et al.
Allergy . 2013 Aug; 68(9):1117-25. PMID: 23915187
Background: House dust mite (HDM) affects the immunological and physical barrier function of airway epithelium, leading to allergic sensitization, airway remodeling, and eosinophilic inflammation in mouse models, although the mechanisms...
18.
Maazi H, Shirinbak S, den Boef L, Fallarino F, Volpi C, Nawijn M, et al.
Clin Exp Immunol . 2013 Mar; 172(1):113-20. PMID: 23480191
Allergen-specific immunotherapy (SIT) is the only treatment for allergic diseases that targets allergen-specific T helper type 2 (Th2) cells, which are the cause of the disease. There is an unmet...
19.
Maazi H, Shirinbak S, Willart M, Hammad H, Cabanski M, Boon L, et al.
Clin Exp Allergy . 2012 Sep; 42(10):1519-28. PMID: 22994349
Background: Allergen-specific immunotherapy (SIT) has been used since 1911, yet its mechanism of action remains to be elucidated. There is evidence indicating that CD4(+)FOXP3(+) regulatory T cells (Treg cells) are...
20.
Bousquet J, Anto J, Demoly P, Schunemann H, Togias A, Akdis M, et al.
Int Arch Allergy Immunol . 2012 Mar; 158(3):216-31. PMID: 22382913
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or...