M C Holden Ko
Overview
Explore the profile of M C Holden Ko including associated specialties, affiliations and a list of published articles.
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7
Citations
156
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Recent Articles
1.
Patrick C, Ko M, Woods J
Analgesia (Elmsford N Y)
. 2011 Sep;
4:397-404.
PMID: 21687823
A recent clinical report suggested that kappa opioids such as nalbuphine and butorphanol produced greater pain relief in women than in men. However, both compounds have been characterized as partial...
2.
Divin M, Ko M, Traynor J
Eur J Pharmacol
. 2008 Feb;
583(1):48-55.
PMID: 18275956
It has been proposed that on chronic morphine treatment the micro-opioid receptor becomes constitutively active, and as a consequence, the opioid withdrawal response arises from a reduction in the level...
3.
Ko M, Wei H, Woods J, Kennedy R
J Pharmacol Exp Ther
. 2006 Jun;
318(3):1257-64.
PMID: 16766718
Nociceptin/orphanin FQ (N/OFQ) is a heptadecapeptide that is an endogenous ligand for the N/OFQ peptide (NOP) receptor. The aim of this study was to investigate the behavioral responses of N/OFQ...
4.
Ko M, Divin M, Lee H, Woods J, Traynor J
J Pharmacol Exp Ther
. 2005 Nov;
316(2):772-9.
PMID: 16258020
6beta-Naltrexol is the major metabolite of the opioid receptor antagonist, naltrexone, in humans. However, there are no functional studies of 6beta-naltrexol in primates. The aim of this study was to...
5.
Neilan C, Husbands S, Breeden S, Ko M, Aceto M, Lewis J, et al.
Eur J Pharmacol
. 2004 Sep;
499(1-2):107-16.
PMID: 15363957
The development of buprenorphine as a treatment for opiate abuse and dependence has drawn attention to opioid ligands that have agonist actions followed by long-lasting antagonist actions. In a search...
6.
Williams K, Ko M, Rice K, Woods J
Psychoneuroendocrinology
. 2003 Apr;
28(4):513-28.
PMID: 12689609
Some opioid antagonists increase the release of adrenocorticotropic hormone (ACTH) and cortisol in humans and, therefore, may indicate that endogenous opioids modulate hypothalamic-pituitary-adrenal axis activity. The type of opioid receptor...
7.
Ko M, Lee H, Song M, Sobczyk-Kojiro K, Mosberg H, Kishioka S, et al.
J Pharmacol Exp Ther
. 2003 Mar;
305(1):173-9.
PMID: 12649366
Pruritus (itch sensation) is the most common side effect associated with spinal administration of morphine given to humans for analgesia. A variety of agents have been proposed as antipruritics with...