M C Garnett
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Explore the profile of M C Garnett including associated specialties, affiliations and a list of published articles.
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51
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Recent Articles
1.
Mansur F, Luoga W, Behnke J, Buttle D, Duce I, Garnett M
Heliyon
. 2021 Oct;
7(10):e08125.
PMID: 34693054
Plant derived cysteine proteinases (CPs) have long been known to possess anthelmintic properties but have attracted renewed attention recently because of the acute need to discover novel methods for controlling...
2.
Mackenzie R, Booth J, Alexander C, Garnett M, Laughton C
J Chem Theory Comput
. 2015 Nov;
11(6):2705-13.
PMID: 26575566
Using a multiscale (dual resolution) approach combining an atomistic (GROMOS96) and coarse-grain (MARTINI) force field, we have been able to simulate the process of drug-polymer nanoparticle assembly by nanoprecipitation from...
3.
Luoga W, Mansur F, Buttle D, Duce I, Garnett M, Lowe A, et al.
J Helminthol
. 2013 Nov;
89(2):165-74.
PMID: 24176056
We examined the in vitro and in vivo efficacy of plant cysteine proteinases (CPs) derived from pineapple (Ananas comosus) and kiwi fruit (Actinidia deliciosa), and compared their efficacy as anthelmintics...
4.
Luoga W, Mansur F, Buttle D, Duce I, Garnett M, Behnke J
J Helminthol
. 2011 Jul;
86(3):311-6.
PMID: 21794201
In earlier studies of the anthelmintic activity of plant cysteine proteinases (CPs), a period of food deprivation was routinely employed before administration of CPs, but there has been no systematic...
5.
Meng W, Kallinteri P, Walker D, Parker T, Garnett M
Exp Biol Med (Maywood)
. 2007 Aug;
232(8):1100-8.
PMID: 17720956
Despite the inherent problems associated with in vivo animal models of tumor growth and metastases, many of the current in vitro brain tumor models also do not accurately mimic tumor-host...
6.
Uptake and metabolism of novel biodegradable poly (glycerol-adipate) nanoparticles in DAOY monolayer
Meng W, Parker T, Kallinteri P, Walker D, Higgins S, Hutcheon G, et al.
J Control Release
. 2006 Nov;
116(3):314-21.
PMID: 17112618
A useful route for the development of antitumour therapies is by creating improved methods for delivering therapeutic agents to tumour cells or subcellular compartments and increasing retention of drugs within...
7.
Garnett M, Kallinteri P
Occup Med (Lond)
. 2006 Jul;
56(5):307-11.
PMID: 16868128
Nanosized materials have been investigated as potential medicines for several decades. Consequently, a great deal of work has been conducted on how to exploit constructs of this size range in...
8.
WINTER J, Davies O, Brown A, Garnett M, Stolnik S, Pritchard D
Parasite Immunol
. 2005 May;
27(4):139-46.
PMID: 15910422
A vaccine against the human hookworm Necator americanus is urgently required to reduce hookworm-induced morbidity in endemic areas. In the present study, recombinant hookworm calreticulin, a nominated vaccine candidate, has...
9.
Stolnik S, Heald C, Neal J, Garnett M, Davis S, Illum L, et al.
J Drug Target
. 2002 Jan;
9(5):361-78.
PMID: 11770706
The micellar-like particle systems produced from poly-D,L-lactide-poly(ethylene glycol) (PLA-PEG) copolymers have been assessed using a range of physicochemical characterisation methods, followed by in vivo studies of their biodistribution after intravenous...
10.
Garnett M
Adv Drug Deliv Rev
. 2001 Dec;
53(2):171-216.
PMID: 11731026
Reports of targeting drugs using antibodies have appeared in the literature since 1958, but exciting clinical results in this field have only been reported in the last few years. Progress...