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M Batke

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Articles 11
Citations 43
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Recent Articles
1.
Rohl C, Batke M, Damm G, Freyberger A, Gebel T, Gundert-Remy U, et al.
Arch Toxicol . 2022 Apr; 96(6):1623-1659. PMID: 35386057
Bromate, classified as a EU CLP 1B carcinogen, is a typical by-product of the disinfection of drinking and swimming pool water. The aim of this study was (a) to provide...
2.
Batke M, Damm G, Foth H, Freyberger A, Gebel T, Gundert-Remy U, et al.
Arch Toxicol . 2022 Feb; 96(4):1133-1135. PMID: 35122513
No abstract available.
3.
Escher S, Mangelsdorf I, Hoffmann-Doerr S, Partosch F, Karwath A, Schroeder K, et al.
Regul Toxicol Pharmacol . 2020 Feb; 112:104584. PMID: 32006672
In human risk assessment, time extrapolation factors (EFs) account for differences in exposure duration of experimental studies. We calculated EFs based on N(L)OEL (no (lowest) observed effect level) ratios, dividing...
4.
Tluczkiewicz I, Kuhne R, Ebert R, Batke M, Schuurmann G, Mangelsdorf I, et al.
Regul Toxicol Pharmacol . 2016 Apr; 78:8-23. PMID: 27041393
The present publication describes an integrative grouping concept to derive threshold values for inhalation exposure. The classification scheme starts with differences in toxicological potency and develops criteria to group compounds...
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Hennes C, Batke M, Bomann W, Duhayon S, Kosemund K, Politano V, et al.
Regul Toxicol Pharmacol . 2014 Aug; 70(2):457-67. PMID: 25092129
Although risk assessment, assessing the potential harm of each particular exposure of a substance, is desirable, it is not feasible in many situations. Risk assessment uses a process of hazard...
7.
Schulz F, Batke M, Mangelsdorf I, Pohlenz-Michel C, Simetska N, Lewin G
Toxicol Lett . 2014 Feb; 226(2):245-55. PMID: 24525464
Numerous studies on reproductive toxicity are expected to be necessary under the EU program on Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). Therefore, it is important to analyse existing...
8.
Batke M, Aldenberg T, Escher S, Mangelsdorf I
Toxicol Lett . 2012 Sep; 218(3):293-8. PMID: 22975263
A common challenge for human risk assessment is the quality of the available animal studies. Non-guideline studies are often limited for different aspects of study design and documentation. Within this...
9.
Batke M, Escher S, Hoffmann-Doerr S, Melber C, Messinger H, Mangelsdorf I
Toxicol Lett . 2011 Jun; 205(2):122-9. PMID: 21640805
In chemical risk assessment for many substances only short-term animal studies are available for the evaluation of long-term human exposure. Therefore usually extrapolation factors (EF) are used to extrapolate NOAELs...
10.
Escher S, Tluczkiewicz I, Batke M, Bitsch A, Melber C, Kroese E, et al.
Regul Toxicol Pharmacol . 2010 Jul; 58(2):259-74. PMID: 20600457
The thresholds of toxicological concern (TTCs) define limit values for substances of unknown toxicity below which dietary intake is considered to be of no concern to human health. The TTC...