M Barbacid
Overview
Explore the profile of M Barbacid including associated specialties, affiliations and a list of published articles.
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Articles
180
Citations
11159
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Recent Articles
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Ambrogio C, Barbacid M, Santamaria D
Oncogene
. 2016 Oct;
36(16):2309-2318.
PMID: 27775074
Activating mutations in KRAS and EGFR, the two most frequent oncogenes in human lung adenocarcinoma, are mutually exclusive, a phenotype attributed to functional redundancy implying lack of positive selection. Employing...
3.
Alvarez R, Musteanu M, Garcia-Garcia E, Lopez-Casas P, Megias D, Guerra C, et al.
Br J Cancer
. 2014 Mar;
111(8):1677-8.
PMID: 24642623
No abstract available.
4.
Alvarez R, Musteanu M, Garcia-Garcia E, Lopez-Casas P, Megias D, Guerra C, et al.
Br J Cancer
. 2013 Aug;
109(4):926-33.
PMID: 23907428
Background: Nab-paclitaxel and gemcitabine have demonstrated a survival benefit over gemcitabine alone in advanced pancreatic cancer (PDA). This study aimed to investigate the clinical, biological, and imaging effects of the...
5.
Drosten M, Lechuga C, Barbacid M
Oncogene
. 2013 Jul;
33(22):2857-65.
PMID: 23831572
Proliferation in the epidermis is a tightly controlled process. During skin development, epidermis formation and hair follicle morphogenesis crucially depend on the regulated balance between proliferation and differentiation. Here we...
6.
Frezzetti D, De Menna M, Zoppoli P, Guerra C, Ferraro A, Bello A, et al.
Oncogene
. 2010 Oct;
30(3):275-86.
PMID: 20956945
miR-21 is a microRNA (miRNA) frequently overexpressed in human cancers. Here we show that miR-21 is upregulated both in vitro and in vivo by oncogenic Ras, thus linking this miRNA...
7.
Boyle P, Anderson B, Andersson L, Ariyaratne Y, Auleley G, Barbacid M, et al.
Ann Oncol
. 2008 Aug;
19(9):1519-21.
PMID: 18723552
No abstract available.
8.
Barbacid M, Ortega S, Sotillo R, Odajima J, Martin A, Santamaria D, et al.
Cold Spring Harb Symp Quant Biol
. 2006 Jul;
70:233-40.
PMID: 16869759
Most human tumors harbor mutations that misregulate the early phases of the cell cycle. Here, we summarize genetic evidence, mostly obtained in our laboratory using strains of gene-targeted mice, that...
9.
Duensing A, Liu Y, Tseng M, Malumbres M, Barbacid M, Duensing S
Oncogene
. 2005 Dec;
25(20):2943-9.
PMID: 16331279
Cyclin-dependent kinase 2 (CDK2) has been proposed to function as a master regulator of centrosome duplication. Using mouse embryonic fibroblasts (MEFs) in which Cdk2 has been genetically deleted, we show...
10.
Marzo N, Mora C, Fabregat M, Martin J, Usac E, Franco C, et al.
Diabetologia
. 2004 Aug;
47(4):686-94.
PMID: 15298346
Aims/hypothesis: Cyclin-dependent kinase 4 (Cdk4) is crucial for beta cell development. A mutation in the gene encoding for Cdk4, Cdk4R24C, causes this kinase to be insensitive to INK4 cell cycle...