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M A Swan

Explore the profile of M A Swan including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 156
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Recent Articles
1.
Ren B, OBrien B, Swan M, Koina M, Nassif N, Wei M, et al.
Diabetologia . 2007 Jun; 50(9):1910-1920. PMID: 17598085
Aims/hypothesis: Type 1 diabetes results from the autoimmune destruction of pancreatic beta cells. Exogenous insulin therapy cannot achieve precise physiological control of blood glucose concentrations, and debilitating complications develop. Lentiviral...
2.
Bezanehtak H, Swan M
J Exp Zool . 1999 Dec; 284(7):789-97. PMID: 10589509
Reactivated movement of the axonemes in demembranated spermatozoa with decondensed nuclei allows decondensation to be monitored in vitro with minimal disruption, and provides access to the nucleus for ultrastructural investigation...
3.
Mortimer S, Swan M
Hum Reprod . 1999 Apr; 14(4):997-1004. PMID: 10221233
It is known that image sampling frequency affects sperm kinematic values, although no study has considered the relative effect upon hyperactivated and non-hyperactivated spermatozoa. We determined the relative effect of...
4.
Mortimer S, Swan M
Hum Reprod . 1999 Apr; 14(4):986-96. PMID: 10221232
The kinematic values which are determined relative to the average path by computer-aided sperm analysis (CASA) instruments are reliant upon the algorithm used for track smoothing, and therefore may differ...
5.
Mortimer S, Swan M, Mortimer D
Hum Reprod . 1998 Oct; 13(8):2139-46. PMID: 9756285
While hyperactivated motility is known to be a concomitant of capacitation, and a prerequisite for fertilization, the specific interdependence of capacitation and hyperactivation in human spermatozoa has not been investigated....
6.
Simpson A, Marshall G, Tuch B, Maxwell L, Szymanska B, Tu J, et al.
Gene Ther . 1998 Jan; 4(11):1202-15. PMID: 9425444
In order to design a feasible somatic cell gene delivery system for the treatment of type I diabetes, a suitable cell type needs to be determined. We have previously shown...
7.
Swan M, Alboghobeish N
J Microsc . 1997 Nov; 187(Pt 3):167-9. PMID: 9351233
Improved preservation of ram spermatozoa was obtained by filtration onto a Millipore filter followed by fixation in a fixative containing 23 mM betaine, which raised fixative osmolality only slightly. In...
8.
Mortimer S, Schevaert D, Swan M, Mortimer D
Hum Reprod . 1997 May; 12(5):1006-12. PMID: 9194655
For technical reasons sperm head movement is assessed in kinematic analysis, while flagellar movement is the determining factor of head movement, not vice versa. It follows then that the development...
9.
Swan M
Int J Androl . 1997 Feb; 20(1):45-54. PMID: 9202990
Improved preservation of the ultrastructural morphology of human spermatozoa was obtained by filtration onto a Millipore filter (0.45 micron pore size) followed by fixation for 1 h in a fixative...
10.
Mortimer S, Swan M, Mortimer D
Hum Reprod . 1996 May; 11(5):1049-54. PMID: 8671389
While head centroid-derived kinematic values have been determined for the trajectories of hyperactivated human spermatozoa, the definitions are not robust with respect to image sampling frequency and track analysis methods....