M A Digman
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Explore the profile of M A Digman including associated specialties, affiliations and a list of published articles.
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8
Citations
188
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Recent Articles
1.
Shiraiwa M, Fang T, Wei J, Lakey P, Hwang B, Edwards K, et al.
Res Rep Health Eff Inst
. 2024 Feb;
(215):1-56.
PMID: 38420854
Introduction: Oxidative stress mediated by reactive oxygen species (ROS) is a key process for adverse aerosol health effects. Secondary organic aerosols (SOA) account for a major fraction of particulate matter...
2.
Digiacomo L, Cardarelli F, Pozzi D, Palchetti S, Digman M, Gratton E, et al.
Nanoscale
. 2017 Nov;
9(44):17254-17262.
PMID: 29115333
Following exposure to biological milieus (e.g. after systemic administration), nanoparticles (NPs) get covered by an outer biomolecular corona (BC) that defines many of their biological outcomes, such as the elicited...
3.
Tan Z, Dai W, van Erp T, Overman J, Demuro A, Digman M, et al.
Mol Psychiatry
. 2015 Jun;
20(11):1286-93.
PMID: 26100538
Huntington's disease (HD), a progressive neurodegenerative disease, is caused by an expanded CAG triplet repeat producing a mutant huntingtin protein (mHTT) with a polyglutamine-repeat expansion. Onset of symptoms in mutant...
4.
Coppola S, Pozzi D, De Sanctis S, Digman M, Gratton E, Caracciolo G
Methods Appl Fluoresc
. 2013 Dec;
1(1).
PMID: 24376913
Spatio-temporal image correlation spectroscopy (STICS) is a powerful technique for assessing the nature of particle motion in complex systems although it has been rarely used to investigate the intracellular dynamics...
5.
Pozzi D, Marchini C, Cardarelli F, Salomone F, Coppola S, Montani M, et al.
Biochim Biophys Acta
. 2013 Dec;
1838(3):957-67.
PMID: 24296066
Here we present a quantitative mechanism-based investigation aimed at comparing the cell uptake, intracellular trafficking, endosomal escape and final fate of lipoplexes and lipid-protamine/deoxyribonucleic acid (DNA) (LPD) nanoparticles (NPs) in...
6.
Marchini C, Pozzi D, Montani M, Alfonsi C, Amici A, De Sanctis S, et al.
Cancer Gene Ther
. 2011 Mar;
18(8):543-52.
PMID: 21394110
Multicomponent lipoplexes have recently emerged as especially promising transfection candidates, as they are from 10 to 100 times more efficient than binary complexes usually employed for gene delivery purposes. Previously,...
7.
Vetri V, Ossato G, Militello V, Digman M, Leone M, Gratton E
Biophys J
. 2011 Feb;
100(3):774-783.
PMID: 21281593
Prefibrillar oligomers of proteins are suspected to be the primary pathogenic agents in several neurodegenerative diseases. A key approach for elucidating the pathogenic mechanisms is to probe the existence of...
8.
Brown C, Dalal R, Hebert B, Digman M, Horwitz A, Gratton E
J Microsc
. 2008 Jan;
229(Pt 1):78-91.
PMID: 18173647
Raster image correlation spectroscopy (RICS) is a new and novel technique for measuring molecular dynamics and concentrations from fluorescence confocal images. The RICS technique extracts information about molecular dynamics and...