Lynn K Pershing
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Explore the profile of Lynn K Pershing including associated specialties, affiliations and a list of published articles.
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10
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96
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Recent Articles
1.
Yacobi A, Shah V, Bashaw E, Benfeldt E, Davit B, Ganes D, et al.
Pharm Res
. 2014 Jan;
31(4):837-46.
PMID: 24395404
This paper summarises the proceedings of a recent workshop which brought together pharmaceutical scientists and dermatologists from academia, industry and regulatory agencies to discuss current regulatory issues and industry practices...
2.
Pershing L, Tirumala V, Nelson J, Corlett J, Lin A, Meyer L, et al.
J Invest Dermatol
. 2008 Jan;
128(7):1633-40.
PMID: 18200057
To date, human skin phototype (SPT) has been determined subjectively by self- or trained investigator assessment using sun burning and/or sun tanning responses, ethnicity, hair, and eye color. This study...
3.
Pershing L, Chen Y, Tkachuk A, Rausch H, Petelenz-Rubin K, Corlett J, et al.
J Invest Dermatol
. 2007 Dec;
128(3):616-27.
PMID: 18049455
Ethanol (EtOH), isopropyl alcohol (IPA), and propylene glycol (PG) increase topical drug delivery, but are sometimes associated with erythema. A potential genetic basis for alcohol-associated erythema was investigated as the...
4.
Pershing L, Nelson J, Corlett J, Bruce Briggs G, Still K, Jederberg W
J Appl Toxicol
. 2006 Jul;
26(5):402-9.
PMID: 16835940
Disposition and uptake/elimination profiles of topical 2,6-di-t-butyl, 4-nitrophenol (DBNP), the nitrated metabolite of an antioxidant additive of lubricant and hydraulic fluids was quantified in human skin grafted on athymic mice...
5.
Pershing L, Reilly C, Corlett J, Crouch D
J Appl Toxicol
. 2005 Oct;
26(1):88-97.
PMID: 16220469
Historically, pepper spray product potency has been established using a taste test evaluation. A taste test is subjective and may not be appropriate for assessing pepper potency in skin. The...
6.
Pershing L, Reilly C, Corlett J, Crouch D
Toxicol Appl Pharmacol
. 2004 Sep;
200(1):73-81.
PMID: 15451310
While the physiologic and molecular effects of capsaicinoids have been extensively studied in various model systems by a variety of administration routes, little is known about the uptake and elimination...
7.
Florell S, Meyer L, Boucher K, Porter-Gill P, Hart M, Erickson J, et al.
J Invest Dermatol
. 2004 Aug;
123(3):576-82.
PMID: 15304099
Phenotypic characteristics of members of a melanoma prone kindred with a V126D CDKN2A gene mutation were monitored over approximately 15 y. Thirty-eight previously studied subjects were recruited. Participants underwent a...
8.
Pershing L, Nelson J, Corlett J, Shrivastava S, Hare D, Shah V
J Am Acad Dermatol
. 2003 May;
48(5):740-51.
PMID: 12734504
Background: A new dermatopharmacokinetic (DPK) approach has been proposed for bioequivalence determination of topical drug products by comparing the drug content kinetics in stratum corneum. Objective: We sought to establish...
9.
Pershing L, Bakhtian S, Poncelet C, Corlett J, Shah V
J Pharm Sci
. 2002 Apr;
91(5):1312-23.
PMID: 11977107
The collective studies compare in vitro drug release, in vivo skin stripping, and skin blanching response methods for dose responsiveness and bioequivalence assessment of triamcinolone acetonide cream products, as a...
10.
Pershing L, Corlett J, Nelson J
Pharm Res
. 2002 Apr;
19(3):270-7.
PMID: 11934233
Purpose: To compare the dermatopharmacokinetic vs. clinical trial methods for bioequivalence assessment of two miconazole nitrate vaginal cream, 2% products. Methods: The dermatopharmacokinetic method determined the bioequivalence of two products...