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Lynn Grignard

Explore the profile of Lynn Grignard including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 938
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Recent Articles
1.
Moreno M, Barry A, Gmeiner M, Yaro J, Serme S, Byrne I, et al.
BMJ Open . 2024 Mar; 14(3):e081682. PMID: 38479748
Introduction: Seasonal malaria chemoprevention (SMC) involves repeated administrations of sulfadoxine-pyrimethamine plus amodiaquine to children below the age of 5 years during the peak transmission season in areas of seasonal malaria...
2.
Fernandez-Camacho B, Pena-Calero B, Guillermo-Roman M, Ruiz-Cabrejos J, Barboza J, Bartolini-Arana L, et al.
Sci Rep . 2024 Feb; 14(1):2806. PMID: 38307878
Despite progress towards malaria reduction in Peru, measuring exposure in low transmission areas is crucial for achieving elimination. This study focuses on two very low transmission areas in Loreto (Peruvian...
3.
Byrne I, William T, Chua T, Patterson C, Hall T, Tan M, et al.
Sci Rep . 2023 Aug; 13(1):12998. PMID: 37563178
Malaysia has reported no indigenous cases of P. falciparum and P. vivax for over 3 years. When transmission reaches such low levels, it is important to understand the individuals and...
4.
Andolina C, Ramjith J, Rek J, Lanke K, Okoth J, Grignard L, et al.
Sci Rep . 2023 May; 13(1):7072. PMID: 37127688
Malaria transmission depends on the presence of Plasmodium gametocytes that are the only parasite life stage that can infect mosquitoes. Gametocyte production varies between infections and over the course of...
5.
Collins K, Ceesay S, Drammeh S, Jaiteh F, Guery M, Lanke K, et al.
J Infect Dis . 2022 Apr; 226(1):128-137. PMID: 35380684
Background: In areas where Plasmodium falciparum malaria is seasonal, a dry season reservoir of blood-stage infection is essential for initiating transmission during the following wet season. Methods: In The Gambia,...
6.
Bareng A, Grignard L, Reyes R, Fornace K, Spencer F, Macalinao M, et al.
Int J Infect Dis . 2021 Dec; 116:174-181. PMID: 34883232
Objective: This study provides 2016 data on the prevalence of key single nucleotide polymorphisms (SNPs) associated with antimalarial drug resistance in Palawan, Philippines. Findings were combined with historical data to...
7.
Barry A, Awandu S, Tiono A, Grignard L, Bousema T, Collins K
Am J Trop Med Hyg . 2021 Nov; 106(2):664-666. PMID: 34724629
We evaluated the detectability of Plasmodium falciparum clones when assessed on 3 consecutive days in incident and chronic infections in naturally exposed children living in an area of intense malaria...
8.
Russell T, Grignard L, Apairamo A, Kama N, Bobogare A, Drakeley C, et al.
Malar J . 2021 Jun; 20(1):248. PMID: 34090430
Background: The Solomon Islands has made significant progress in the control of malaria through vector control, access and use of improved diagnostics and therapeutic drugs. As transmission is reduced there...
9.
Barry A, Bradley J, Stone W, Guelbeogo M, Lanke K, Ouedraogo A, et al.
Nat Commun . 2021 Apr; 12(1):2443. PMID: 33903595
Plasmodium falciparum gametocyte kinetics and infectivity may differ between chronic and incident infections. In the current study, we assess parasite kinetics and infectivity to mosquitoes among children (aged 5-10 years)...
10.
Sepulveda N, Grignard L, Curry J, Mahey L, Bastiaens G, Tiono A, et al.
Front Genet . 2021 Apr; 12:645688. PMID: 33897764
Primaquine (PQ) is an antimalarial drug with the potential to reduce malaria transmission due to its capacity to clear mature gametocytes in the human host. However, the large-scale roll-out of...