Lyman W Whitlatch
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Explore the profile of Lyman W Whitlatch including associated specialties, affiliations and a list of published articles.
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6
Citations
108
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Recent Articles
1.
Flanagan J, Young M, Persons K, Wang L, Mathieu J, Whitlatch L, et al.
Anticancer Res
. 2006 Aug;
26(4A):2567-72.
PMID: 16886665
Background: Prostate cells can produce 1alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)2D3) from 25-hydroxyvitamin D3 (25(OH)D3) to regulate their own growth. Here, the questions of whether prostate cells express vitamin D-25-hydroxylase (25-OHase) and can...
2.
Wang L, Flanagan J, Whitlatch L, Jamieson D, Holick M, Chen T
J Steroid Biochem Mol Biol
. 2004 Jul;
89-90(1-5):127-30.
PMID: 15225759
Accumulating data suggest that local production of 1alpha,25-dihydroxyvitamin D (1alpha,25(OH)(2)D) could provide an important cell growth regulatory mechanism in an autocrine fashion in prostate cells. Previously, we demonstrated a differential...
3.
Young M, Schwartz G, Wang L, Jamieson D, Whitlatch L, Flanagan J, et al.
Carcinogenesis
. 2004 Jan;
25(6):967-71.
PMID: 14729578
The hormonal form of vitamin D, 1 alpha,25-dihydroxyvitamin D [1 alpha,25(OH)(2)D] promotes the differentiation and inhibits the proliferation, invasiveness and metastasis of prostate cells. However, 1 alpha,25(OH)(2)D is not suitable...
4.
Wang L, Whitlatch L, Flanagan J, Holick M, Chen T
Recent Results Cancer Res
. 2003 Aug;
164:223-37.
PMID: 12899525
25-Hydroxyvitamin D-1alpha-hydroxylase (lalpha-OHase) is expressed in prostate cells. The expression suggests that local production of 1,25-dihydroxyvitamin D could provide an important cell growth regulatory mechanism. However, there is differential expression...
5.
Chen T, Wang L, Whitlatch L, Flanagan J, Holick M
J Cell Biochem
. 2003 Jan;
88(2):315-22.
PMID: 12520532
Evidence suggests that vitamin D may have a protective role for prostate cancer. 1alpha,25-Dihydroxyvitamin D [1alpha,25(OH)(2)D] inhibits growth and induces differentiation of prostate cells. 25-Hydroxyvitamin D-1alpha-hydroxylase [1alpha-OHase], the enzyme that...
6.
Whitlatch L, Young M, Schwartz G, Flanagan J, Burnstein K, Lokeshwar B, et al.
J Steroid Biochem Mol Biol
. 2002 Jul;
81(2):135-40.
PMID: 12137802
The hormone 1alpha,25-dihydroxyvitamin D (1alpha,25(OH)(2)D) inhibits growth and induces differentiation of prostate cells. The enzyme responsible for 1alpha,25(OH)(2)D synthesis, 25-hydroxyvitamin D (25(OH)D)-1alpha-hydroxylase (1alpha-OHase), has been demonstrated in human prostate cells....