Lydia Sorokin
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Explore the profile of Lydia Sorokin including associated specialties, affiliations and a list of published articles.
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94
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5025
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Recent Articles
1.
Deshpande T, Hannocks M, Kapupara K, Samawar S, Wachsmuth L, Faber C, et al.
Neuropathol Appl Neurobiol
. 2024 Nov;
50(6):e13015.
PMID: 39543785
Aims: Cerebral small vessel diseases (SVDs) involve diverse pathologies of the brain's small blood vessels, leading to cognitive deficits. Cerebral magnetic resonance imaging (MRI) reveals white matter hyperintensities (WMHs), lacunes,...
2.
Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
Park H, Song J, Jeong H, Gronloh M, Koh B, Bovay E, et al.
Nat Commun
. 2024 Jul;
15(1):6282.
PMID: 39060233
Demyelination due to autoreactive T cells and inflammation in the central nervous system are principal features of multiple sclerosis (MS), a chronic and highly disabling human disease affecting brain and...
3.
Denes A, Hansen C, Oezorhan U, Figuerola S, de Vries H, Sorokin L, et al.
Acta Neuropathol
. 2024 Feb;
147(1):38.
PMID: 38347307
Diseases of the central nervous system (CNS) are often associated with vascular disturbances or inflammation and frequently both. Consequently, endothelial cells and macrophages are key cellular players that mediate pathology...
4.
The niche matters: origin, function and fate of CNS-associated macrophages during health and disease
Dalmau Gasull A, Glavan M, Samawar S, Kapupara K, Kelk J, Rubio M, et al.
Acta Neuropathol
. 2024 Feb;
147(1):37.
PMID: 38347231
There are several cellular and acellular structural barriers associated with the brain interfaces, which include the dura, the leptomeninges, the perivascular space and the choroid plexus epithelium. Each structure is...
5.
Sorokin L, Correa L
Methods Mol Biol
. 2023 Aug;
2713:307-322.
PMID: 37639132
The adipose tissue comprises highly heterogeneous macrophage populations, which play critical roles in the regulation of adipose tissue function and dysfunction during health and disease. Whole-amount staining is a powerful...
6.
Burmeister M, Frauenstein A, Kahms M, Arends L, Gerwien H, Deshpande T, et al.
Sci Adv
. 2023 Jul;
9(29):eadg0686.
PMID: 37467333
The gelatinases, matrix metalloproteinase 2 (MMP-2) and MMP-9, are key for leukocyte penetration of the brain parenchymal border in neuroinflammation and the functional integrity of this barrier; however, it is...
7.
Luik A, Hannocks M, Loismann S, Kapupara K, Cerina M, van der Stoel M, et al.
Matrix Biol
. 2023 Jun;
121:56-73.
PMID: 37311512
Basement membranes (BMs) are critical but frequently ignored components of the vascular system. Using high-resolution confocal imaging of whole-mount-stained mesenteric arteries, we identify integrins, vinculin, focal adhesion kinase (FAK) and...
8.
Paul Konken C, Beutel B, Schinor B, Song J, Gerwien H, Korpos E, et al.
Bioorg Med Chem
. 2023 Jun;
90:117350.
PMID: 37270903
To develop matrix metalloproteinase inhibitors (MMPIs) for both therapy and medicinal imaging by fluorescence-based techniques or positron-emission tomography (PET), a small library of eighteen N-substituted N-arylsulfonamido d-valines were synthesized and...
9.
Song J, Deshpande T, Zhang X, Hannocks M, Lycke N, Cardell S, et al.
iScience
. 2023 May;
26(5):106753.
PMID: 37234087
Germinal center (GC) formation and antibody production in lymph node follicles require coordinated interactions between B-cells, T-cells and dendritic cells (DCs), orchestrated by the extracellular matrix-rich reticular fiber (RF) network....
10.
Xue Y, Lin L, Li Q, Liu K, Hu M, Ye J, et al.
Adv Sci (Weinh)
. 2022 Dec;
10(4):e2201949.
PMID: 36507562
Niche for stem cells profoundly influences their maintenance and fate during tissue homeostasis and pathological disorders; however, the underlying mechanisms and tissue-specific features remain poorly understood. Here, it is reported...